Apd668 4-((1-(2-氟-4-(甲基磺酰基)苯基)-1H-吡唑并[3,4-d]嘧啶-4-基)氧基)哌啶-1-甲酸异丙酯
CAS 832714-46-2 MFCD12032117
化学结构图
SMILES: CC(C)OC(=O)N1CCC(CC1)OC1=NC=NC2=C1C=NN2C1C=CC(=CC=1F)S(C)(=O)=O
化学属性
| Mol. Formula | C21H24FN5O5S |
|---|---|
| Mol. Weight | 477.515 |
别名和识别编码
| Chemical Name | Apd668 |
|---|---|
| Chemical Name Translation | 4-((1-(2-氟-4-(甲基磺酰基)苯基)-1H-吡唑并[3,4-d]嘧啶-4-基)氧基)哌啶-1-甲酸异丙酯 |
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相关文献及参考
- [2]. Bahirat UA, et, al. APD668, a G protein-coupled receptor 119 agonist improves fat tolerance and attenuates fatty liver in high-trans fat diet induced steatohepatitis model in C57BL/6 mice. Eur J Pharmacol. 2017 Apr 15;801:35-45.
- [1]. Semple G, et al. Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control. Bioorg Med Chem Lett. 2011 May 15;21(10):3134-41.
- [1]. Semple G, et al. Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control. Bioorg Med Chem Lett. 2011 May 15;21(10):3134-41.
- [2]. Bahirat UA, et, al. APD668, a G protein-coupled receptor 119 agonist improves fat tolerance and attenuates fatty liver in high-trans fat diet induced steatohepatitis model in C57BL/6 mice. Eur J Pharmacol. 2017 Apr 15;801:35-45.
