Sultamicillin Tosilate 对甲苯磺酸舒他西林
CAS 83105-70-8 MFCD01682151
化学结构图
SMILES: CC1C=CC(=CC=1)S(O)(=O)=O.CC1(C)[C@H](C(=O)OCOC(=O)[C@@H]2N3[C@@H](CC3=O)SC2(C)C)N2[C@@H]([C@H](NC(=O)[C@H](N)C3C=CC=CC=3)C2=O)S1(=O)=O
化学属性
| Mol. Formula | C25H30N4O9S2.C7H8O3S |
|---|---|
| Mol. Weight | 767 |
| Density | |
| Boiling Point | |
| Melting Point |
别名和识别编码
| Chemical Name | Sultamicillin Tosilate |
|---|---|
| Synonym | CP 49952 p-Toluenesulfonate Sbtpc Sultamicillin tosilate Sultamicillin tosylate VD 1827 p-Toluenesulfonate |
| CAS Number | 83105-70-8 |
| EC Number | |
| Beilstein Registry Number | |
| Chemical Name Translation | 对甲苯磺酸舒他西林 |
| Reaxys-RN | 25499733 |
| MDL Number | MFCD01682151 |
| PubChem Substance ID | 354335315 |
| Merck Number | 8992 |
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TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3181 mg/kg TOXIC EFFECTS : Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis Nutritional and Gross Metabolic - body temperature decrease REFERENCE : NKRZAZ Chemotherapy (Tokyo). (Nippon Kagaku Ryoho Gakkai, 2-20-8 Kamiosaki, Shinagawa-Ku, Tokyo 141, Japan) V.1- 1953- Volume(issue)/page/year: 33(Suppl 2),102,19
{hazard_cTYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >10 gm/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) REFERENCE : NKRZAZ Chemotherapy (Tokyo). (Nippon Kagaku Ryoho Gakkai, 2-20-8 Kamiosaki, Shinagawa-Ku, Tokyo 141, Japan) V.1- 1953- Volume(issue)/page/year: 33(Suppl 2),102,1985
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2356 mg/kg TOXIC EFFECTS : Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis Nutritional and Gross Metabolic - body temperature decrease REFERENCE : NKRZAZ Chemotherapy (Tokyo). (Nippon Kagaku Ryoho Gakkai, 2-20-8 Kamiosaki, Shinagawa-Ku, Tokyo 141, Japan) V.1- 1953- Volume(issue)/page/year: 33(Suppl 2),102,1985
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,608,1995
TYPE OF TEST : LD50
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 44400 mg/kg
SEX/DURATION : male 63 day(s) pre-mating
female 7-17 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4
per # born alive)
REFERENCE :
NKRZAZ Chemotherapy (Tokyo). (Nippon Kagaku Ryoho Gakkai, 2-20-8 Kamiosaki,
Shinagawa-Ku, Tokyo 141, Japan) V.1- 1953- Volume(issue)/page/year:
33(Suppl 2),112,1985 GHS Symbol
