YC-137 is a BCL-2 inhibitor, which selectively induces apoptosis of Bcl-2-overexpressing cells and disrupts its interaction with Bid BH3, thereby blocking the anti-apoptotic activity of Bcl-2.
CAS 810659-53-1 MFCD10659531
化学结构图
SMILES: COC(=O)NC(CCSC)C(=O)Oc1ccc(Nc2nc3c(s2)C(=O)c2ccccc2C3=O)cc1
化学属性
| Mol. Weight | 511.57 |
|---|---|
| Appearance | White to off-white solid powder. |
| Solubility | Soluble in DMSO, not in water |
别名和识别编码
| Chemical Name | YC-137 is a BCL-2 inhibitor, which selectively induces apoptosis of Bcl-2-overexpressing cells and disrupts its interaction with Bid BH3, thereby blocking the anti-apoptotic activity of Bcl-2. |
|---|---|
| Formula | C24H21N3O6S2 |
| Synonym | YC137; YC 137; YC137. |
| IUPAC Name | 4-((4,9-dioxo-4,9-dihydronaphtho[2,3-d]thiazol-2-yl)amino)phenyl 2-((methoxycarbonyl)amino)-4-(methylthio)butanoate |
| InChIKey | SFDSXIZFOOBDMC-UHFFFAOYSA-N |
| InChI | InChI=1S/C24H21N3O6S2/c1-32-24(31)26-17(11-12-34-2)22(30)33-14-9-7-13(8-10-14)25-23-27-18-19(28)15-5-3-4-6-16(15)20(29)21(18)35-23/h3-10,17H,11-12H2,1-2H3,(H,25,27)(H,26,31) |
| Canonical SMILES | O=C(OC1=CC=C(NC2=NC(C3=O)=C(C(C4=C3C=CC=C4)=O)S2)C=C1)C(NC(OC)=O)CCSC |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
产品应用
- YC-137 is a BCL-2 inhibitor, which selectively induces apoptosis of Bcl-2-overexpressing cells and disrupts its interaction with Bid BH3, thereby blocking the anti-apoptotic activity of Bcl-2.
