CAS 8003-34-7 MFCD00078611-Pyrethrum extract 除虫菊提取物 TAO{mole}

Pyrethrum extract 除虫菊提取物

CAS 8003-34-7 MFCD00078611

化学结构图

SMILES: C=C/C=C/CC1=C(C)C(OC(=O)[C@@H]2C(/C=C(\C)C(=O)OC)C2(C)C)CC1=O.C=C/C=C/CC1=C(C)[C@@H](OC(=O)[C@@H]2C(C=C(C)C)C2(C)C)CC1=O

化学属性

Mol. Formula	C43H56O8
Mol. Weight	700.90
Refractive index	n20/D 1.45
Flash Point	75 ºC
Solubility	不溶于水，溶于多数有机溶剂。

别名和识别编码

Chemical Name	Pyrethrum Extract (Technical Grade)
MDL Number	MFCD00078611
CAS Number	8003-34-7
EC Number	232-319-8
Synonym	pyrethre Prentox pyrethrum extract 除虫菊提取物 pyrethriniorii pyrenone Firmotox Pyrethrin I or II 除虫菊 insectpowder Jasmolin I or II pyrethrines Buhach firmotox PYRETHRINS dalmatianinsectpowder dalmationinsectflowers CHECKOUT jasmoliniorii Insect powder Pyrethrum prentoxpyrethrumextract persianinsectpowder cineriniorii PYRETHRUM 除虫菊酯类 Cinerin I or II Dalmation insect flowers buhach insecticides,pyrethrins Chrysanthemum cinerareaefolium 除虫菊酯 WOPROTHRUM Trieste flowers PYRETHRUM-EXTRACT Pyrocide chrysanthemumcinerareaefolium Pyrethrins Pyronyl Pyrenone Pyrethrum (insecticide)
Chemical Name Translation	除虫菊提取物
Wiswesser Line Notation	L5V BUTJ B2U2U1 C1 DOV- BL3TJ A1 A1 C1U2

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

安全信息

GHS Symbol

WGK Germany3

Precautionary statements

P501 Dispose of contents/container to..… 处理内容物/容器.....
P273 Avoid release to the environment. 避免释放到环境中。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。

Hazard statements

H332 Harmful if inhaled 吸入有害
H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
H302 Harmful if swallowed 吞食有害
H312 Harmful in contact with skin 皮肤接触有害

RTECSUR4200000

Signal word Warning

Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

Hazard Codes Xn;N Xn,N

Safety Statements

S13 Keep away from food, drink and animal foodstuffs 远离食品、饮料和动物饲料保存；
S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；

Risk Statements

R50/53
R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害

UN Number 2810 UN 2810 6.1/PG 3

Storage condition 2-8°C

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GUCHAZ Guide to the Chemicals Used in Crop Protection.  (Information Canada,
   171 Slater St., Ottawa, Ont., Canada)  Volume(issue)/page/year: 6,442,1973

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1350 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YKYUA6 Yakkyoku.  Pharmacy.  (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo,
   Japan)  V.1-    1950-  Volume(issue)/page/year: 37,1481,1986

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   WRPCA2 World Review of Pest Control.  (London, UK)  V.1-10, 1962-71.
   Discontinued.  Volume(issue)/page/year: 3,28,1964

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - child
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CMEP** "Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public
   Health Service, Communicable Disease Center, Atlanta, GA, 1956
   Volume(issue)/page/year: -,1,1956

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 250 mg/kg
TOXIC

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 500 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 10,111,1982

其他信息

除虫菊酯中毒:除虫菊为菊科植物白花除虫菊的干燥花序，约含1%除虫菊酯，具有杀虫药效好、击倒快、低毒等优点。近年来人工合成除虫菊酯类似物，具有杀虫谱广、对人畜毒性较低、环境残留较少等优点，故称其为拟除虫菊酯类杀虫药。本类杀虫药均属神经毒剂。目前市售实用产品有20余种，我国主要应用溴氰菊酯、氰戊菊酯、氯氰菊酯、氯菊酯、胺菊酯等，均属口服吸收毒性较大的中等毒性产品。本类杀虫药中多含除虫菊酯增效剂 (P-450细胞色素抑制剂)。家庭用杀虫剂为除虫菊酯类药与其他成分的混合物。除虫菊酯虽为低毒杀虫剂，但与其他杀虫剂，如灭虫菊、普鲁本辛酚等合用，可明显增强其毒性，或延长药物的半衰期。本类杀虫剂吸入毒性强。中毒机理：除虫菊酯可使机体神经细胞膜发生轻度去极化，增加复后电位，导致重复性后放电，影响Na+、K+通道，阻断运动电位而致发中毒。除虫菊酯增效剂能抑制和延缓除虫菊酯在机体内的代谢，增强其毒性和延长体内药物作用时间而提高药效。
MOL 文件:8003-34-7.mol
杀虫剂:除虫菊酯是制备蚊虫香的主要原料，为菊科多年生草本植物除虫菊内所含的杀虫有效成分。主要有除虫菊酯Ⅰ和除虫菊酯Ⅱ，另外还有少量结构近似的瓜叶除虫菊酯Ⅰ、瓜叶除虫菊酯Ⅱ等。目前已人工合成多种与天然除虫菊酯类似的化合物用作杀虫剂，统称为拟除虫菊酯。除虫菊酯为黄色粘稠油状液体，有清香气味。不溶于水，可溶于多种有机溶剂。不稳定，遇碱分解失效，在强光或高温下也分解失效。主要剂型有粉剂、乳油、气雾剂、油剂、蚊香等。有强力触杀作用，杀虫谱广。残效期短。主要用于防治卫生害虫、家畜害虫等。对人畜非常安全，对植物无药害、无残留，不污染农产品和环境的植物源农药。对温血动物安全。对昆虫的毒力强度，以除虫菊酯Ⅰ最强，瓜叶除虫菊酯1次之，除虫菊酯Ⅱ再次之，瓜叶除虫菊酯Ⅱ最弱。FAO/WHO建议日容许摄入量为0.04mg/kg体重 (包括其它除虫菊酯)。大鼠口服1500mg/kg。食品中最高容许浓度：瑞典规定水果和蔬菜为1.0mg/kg(包括除虫菊酯Ⅰ)；FAO/WHO建议鱼(干)、未加工谷类为3mg/kg，干果、干蔬菜、鲜果和鲜蔬菜、花生米、核果为1mg/kg(包括其他除虫菊酯)。图1为除虫菊素主要成分除虫菊酯Ⅰ和除虫菊酯Ⅱ的化学结构式以上信息由Chemicalbook的晓楠编辑整理。
RTECS号:UR4200000
外观性质:黄色粘稠液体，含有五种有效成份。
PackingGroup:III
HazardClass:6.1(b)
除虫菊酯和拟除虫菊酯:除虫菊酯是干菊花的提取物，因为其在热和光条件下还是很稳定，所以主要被用于室内杀虫剂。一些杀灭头虱的洗发水也含有除虫菊酯。拟除虫菊酯是在除虫菊酯结构和生物活性基础上人工合成的，其稳定性得到了增加，主要分成类型Ⅰ和类型Ⅱ，类型Ⅱ的毒性大于类型Ⅰ。合成除虫菊酯在农业以及园艺上主要用于杀灭建筑害虫 (如白蚁)、虱子和跳蚤。除虫菊酯及合成除虫菊酯可以迅速渗透至害虫体内，使其瘫痪。氯菊酯是研究较早的一种不含氰基结构的拟除虫菊酯类杀虫剂，是菊酯类农药中第1个出现适用于防治农业害虫的光稳定性杀虫剂。