DALTROBAN
CAS 79094-20-5 MFCD00868295
化学结构图
SMILES: OC(=O)CC1C=CC(CCNS(=O)(=O)C2C=CC(Cl)=CC=2)=CC=1
化学属性
| Mol. Formula | C16H16ClNO4S |
|---|---|
| Mol. Weight | 353.82 |
| Melting Point | 132.5-137.4 °C (lit.) |
别名和识别编码
| Chemical Name | Daltroban |
|---|---|
| Synonym | 4-[2-[(4-Chlorophenylsulfonyl)amino]ethyl]benzeneacetic acid 4-[2-[(4-Chlorophenylsulfonyl)amino]ethyl]benzeneacetic acid BM-13505 SKF-96148 BM-13505 SKF-96148 |
| MDL Number | MFCD00868295 |
| PubChem Substance ID | 24724468 |
| CAS Number | 79094-20-5 |
信息真实价格透明
资金保障
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信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, D-DIF, Lipids in Cell Signaling, Prostaglandins, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- Analytical Standards, Analytical/Chromatography, Arachidonic Acid Cascade, Bioactive Small Molecules, Cell
相关文献及参考
- [2]. Thiemermann C, et al. The thromboxane receptor antagonist, daltroban, protects the myocardium from ischaemic injury resulting in suppression of leukocytosis. Eur J Pharmacol. 1988 Oct 11;155(1-2):57-67.
- [3]. Bhat AM, et al. Protective effect of the specific thromboxane receptor antagonist, BM-13505, in reperfusion injury following acute myocardial ischemia in cats. Am Heart J. 1989 Apr;117(4):799-803.
- Mais, D.E. et al, Thromboxane A2 antagonists. Synthesis and activities of phenylsulfonamido derivatives. Eur. J. Med. Chem. 26 , 821-827, (1991)
- Merck 14 ,2806
- Schieferdecker, H.L., et. al, Induction of functional anaphylatoxin C5a receptors on hepatocytes by in vivo treatment of rats with IL-6. J. Immunol. 164 , 5453-5458 , (2000) 摘要
- [1]. Miki I, et al. Differences in acti
- [1]. Miki I, et al. Differences in activities of thromboxane A2 receptor antagonists in smooth muscle cells. Eur J Pharmacol. 1992 Oct 1;227(2):199-204.
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
