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• 试剂商城
• 直接询价

分类

• Amines
• Heterocycles
• Pharmaceuticals
• Intermediates & Fine Chemicals
• {uni_hamburg} no charge; nitrogen heterocycle; alicycle; 6RingOnly; 6ring; urea; amide; lactame; 1fragment
• {SA} Alphabetic, Analytical Standards, Analytical/Chromatography, B, BI - BZ, Chromatography, Drugs & Metabolites, Forensic and Veterinary Standards, Neat Compounds
• {SNA} Alphabetic, Analytical Standards, Analytical/Chromatography, B, BI - BZ

产品应用

• Controlled substance (depressant). Sedative, hypnotic.

相关文献及参考

• Inaba, T., et al.: Clin. Pharmacol. Ther., 18, 558 (1975),
• Fritch, D., et al.: J. Anal. Toxicol., 33, 569 (2009),
• Wille, S., et al.: Ther. Drug Monit., 31, 511 (2009),
• Short: IV/1a Title: Densities of Liquid Systems: Nonaqueous Systems and Ternary Aqueous Systems Author: Lacmann, R.; Synowietz, C. Editor: Schäfer, Kl. Source: Landolt-Börnstein, New Series Volume: IV/1a Year: 1974 ISBN: 3-540-06269-6 ISBN: 978-3-540-06269-1 Internet Resource: DOI:10.1007/b20003 RefComment: X, 716 pages. Hardcover Abstract: Volume IV/1 contains information on the densities of liquid systems. It may be considered as a supplement to volume II/1 of the 6th Edition, which contains only a few data on nonaqueous systems. Data are not listed for all systems but primarily for those of greater interest where data for a larger range of concentrations were available.
• Short: EINECS Title: EINECS (European Inventory of Existing Commercial Chemical Substances) Source: Official Journal of the European Communities Volume: C 146 A (15.06.1990) Page: 1 Year: 1990 Internet Resource: http://ecb.jrc.ec.europa.eu/esis/index.php?PGM=ein Publish_Date: 1990/06/15

安全信息

GHS Symbol

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Vascular - BP lowering not characterized in autonomic section
   Lungs, Thorax, or Respiration - respiratory depression
   Gastrointestinal - nausea or vomiting
REFERENCE :
   SAVEAB Sammlung von Vergiftungsfaellen.  (Berlin, Germany)  V.1-13, 1930-44;
   V.14, 1952-54.  For publisher information, see ARTODN.
   Volume(issue)/page/year: 10,181A,1939

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - child
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Behavioral - toxic psychosis
   Behavioral - coma
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   SAVEAB Sammlung von Vergiftungsfaellen.  (Berlin, Germany)  V.1-13, 1930-44;
   V.14, 1952-54.  For publisher information, see ARTODN.
   Volume(issue)/page/ye

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - pigeon
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   21,315,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 160 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 152,341,1930