Mepenzolate Bromide 溴美喷酯

CAS 76-90-4 MFCD00079450

化学结构图

76-90-4
SMILES: C[N+]1(C)CCCC(OC(=O)C(O)(c2ccccc2)c2ccccc2)C1.[Br-]

化学属性

Mol. FormulaC21H26BrNO3
Mol. Weight420

别名和识别编码

Chemical NameMepenzolate Bromide
CAS Number76-90-4
Synonym N-Methyl-3-piperidyl benzilate methobromide Benzilic acid, 1-methyl-3-piperidyl ester methobromide Cantril 溴美喷酯 3-((Hydroxydiphenylacetyl)oxy)-1,1-dimethylpiperidinium bromide 溴化甲呱佐酯 Benzilic acid, ester with 3-hydroxy-1,1-dimethylpiperidinium bromide Mepenzolate bromide N-Methyl-3-piperidyl benzilate methyl bromide 3-Hydroxy-1,1-dimethylpiperidinium bromide benzilate 溴美喷酯; 溴化甲呱佐酯 Mepenzolate Trancolon 3-[(Hydroxy-diphenylacetyl)oxy]-1,1-dimethylpiperidinium Bromide Cantil JB 340 Gastropidil N-Methyl-3-piperidyldiphenylglycolate methobromide
MDL NumberMFCD00079450
EC Number200-992-7
PubChem Substance ID6461
Chemical Name Translation溴美喷酯
Wiswesser Line NotationT6KTJ A1 A1 COVXQR&R &E
LabNetwork Molecule IDLN00201424
InChIInChI=1S/C21H26NO3.BrH/c1-22(2)15-9-14-19(16-22)25-20(23)21(24,17-10-5-3-6-11-17)18-12-7-4-8-13-18;/h3-8,10-13,19,24H,9,14-16H2,1-2H3;1H/q+1;/p-1
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分类

  • Pharmaceuticals
  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Chromatography, Drugs & Metabolites, Forensic and Veterinary Standards, M, MEA - MES, Neat Compounds
  • Intermediates & Fine Chemicals,

产品应用

  • Used as an anticholinergic

相关文献及参考

  • Goldenthal, E.I.: Toxicol. Appl. Pharmacol., 18, 185 (1971)

安全信息

RTECSTN5710000
GHS Symbol
Signal word Warning
Hazard statements
  • H302 Harmful if swallowed 吞食有害
WGK Germany3
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Hazard Codes Xn
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 88 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,358,1982

{h

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZIAQ "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes,
   C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973
   Volume(issue)/page/year: -,148,1973

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 22

TYPE OF TEST

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 158 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,358,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 740 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   18,185,1971

系列性分类


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