CBZ-LLE BETA-NAPHTHYLAMINE
CAS 75873-85-7 MFCD00058505
化学结构图
SMILES: CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCC1C=CC=CC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)NC1C=C2C=CC=CC2=CC=1
化学属性
| Mol. Formula | C35H44N4O7 |
|---|---|
| Mol. Weight | 632.75 |
别名和识别编码
| Chemical Name | Z-Leu-Leu-Glu β-naphthylamide |
|---|---|
| Synonym | Cbz-LLE β-naphthylamine Cbz-LLE β-naphthylamine |
| MDL Number | MFCD00058505 |
| PubChem Substance ID | 24892275 |
| CAS Number | 75873-85-7 |
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分类
- {SA} Application Index, Bioactive Small Molecules, Biochemicals and Reagents, Calpain and Proteasome Inhibitors, Cell Biology, Cell Signaling Enzymes,
- Application Index, Bioactive Small Molecules, Biochemicals and Reagents, Calpain and Proteasome Inhibitors, Cell Biology, Cell Signaling Enzymes,
相关文献及参考
- Cardozo, C., Catalytic components of the bovine pituitary multicatalytic proteinase complex (proteasome). Enzyme Protein 47 , 296, (1993) 摘要
- Realini, C., et al., Characterization of recombinant REGα, REGβ, and REGγ proteasome activators. J. Biol. Chem. 272 , 25483, (1997) 摘要
- Djaballah, H., and Rivett, A.J., Peptidylglutamyl-peptide hydrolase activity of the multicatalytic proteinase complex: evidence for a new high-affinity site. Biochemistry 31 , 4133-4141, (1992) 摘要
- Wilk, S. and Orlowsk, M., Evidence that pituitary cation-sensitive neutral endopeptidase is a multicatalytic protease complex. J. Neurochem. 40 , 842-849, (1983) 摘要
- Zhang, J., et al., Activation Of GluR6-containing Kainate Receptors Induces Ubiquitin-dependent Bcl-2 Degradation Via Denitrosylation In The Rat Hippocampus After Kainate Treatment. J. Thorac. Cardiovasc. Surg. 286 , 7669-80, (2011) 摘要
安全信息
GHS Symbol
- P281 Use personal protective equipment as required. 使用所需的个人防护装备。
- H351 Suspected of causing cancer 怀疑致癌
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- S22 Do not breathe dust 不要吸入粉尘；
- R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
