4-Chloro-N-(4,5-Dihydro-1H-Imidazol-2-Yl)-6-Methoxy-2-Methylpyrimidin-5-Amine 4-氯-N-(4,5-二氢-1H-咪唑-2-基)-6-甲氧基-2-甲基嘧啶-5-胺
CAS 75438-57-2 MFCD75438572
化学结构图
SMILES: CC1N=C(Cl)C(NC2NCCN=2)=C(N=1)OC
化学属性
| Mol. Weight | 241.68 |
|---|---|
| Mol. Formula | C9H12ClN5O |
别名和识别编码
| CAS Number | 75438-57-2 |
|---|---|
| Chemical Name | 4-Chloro-N-(4,5-Dihydro-1H-Imidazol-2-Yl)-6-Methoxy-2-Methylpyrimidin-5-Amine |
| Synonym | 4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine 2-(6-Chloro-4-methoxy-2-methylpyrimidin-5-ylamino)-2-imidazoline Lomox Moxon Norcynt Normoxocin Nucynt Physiotens |
| Chemical Name Translation | 4-氯-N-(4,5-二氢-1H-咪唑-2-基)-6-甲氧基-2-甲基嘧啶-5-胺 |
| MDL Number |
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分类
- Aromatics
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
- Moxonidine is an antihypertensive agent.
相关文献及参考
- [2]. Chan, C.K., et al., Imidazoline receptors associated with noradrenergic terminals in the rostral ventrolateral medulla mediate the hypotensive responses of moxonidine but not clonidine. Neuroscience, 2005. 132(4): p. 991-1007.
- Nasr, M., et al.: Vas. Pharmacol., 53, 53 (2010),
- Rayment, S., et al.: Brit. J. Pharmacol., 160, 1727 (2010),
- Taksande, B., et al.: Eur. J. Pharmacol., 637, 89 (2010),
- [1]. Schafer, U., et al., Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of imidazoline-1 receptors and alpha2-adrenoceptors. J Pharmacol Exp Ther, 2002. 303(3): p. 1163-70.
- [1]. Schafer, U., et al., Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of imidazoline-1 receptors and alpha2-adrenoceptors. J Pharmacol Exp Ther, 2002. 303(3): p. 1163-70.
- [2]. Chan, C.K., et al., Imidazoline receptors associated with noradrenergic terminals in the rostral ventrolateral medulla mediate th
