Propylene oxide 环氧丙烷
CAS 75-56-9 MFCD00005126
信息真实价格透明
资金保障
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信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {uni_hamburg} no charge; oxygen heterocycle; alicycle; 3ring; ether; racemate; 1fragment
- {SA} Building Blocks, Chemical Synthesis, Epoxide Monomers, Epoxides, Materials Science, Monomers, Organic Building Blocks, Oxygen Compounds, Polymer Science
- {SNA} Building Blocks, Chemical Synthesis, Epoxide Monomers,
产品应用
- 环氧丙烷是重要的有机化工原料,为丙烯系的第三大产品,最大用途是制聚多元醇(聚醚),进而制造聚氨酯.
- 环氧丙烷用于制取非离子表面活性剂和丙烯醇、丙二醇、异丙醇胺、丙醛、合成甘油、有机酸、合成树脂、泡沫塑料、增塑剂、乳化剂、湿润剂、洗涤剂、杀菌剂、熏蒸剂等。
相关文献及参考
- Merck: 14,7856 Beilstein:17,6
- Merck: 14,7856
- Short: II/19b
- Short: II/14a
安全信息
GHS Symbol
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
- R46 May cause inheritable genetic damage 可能引起遗传基因损害
- R12 Extremely flammable 极端易燃
- R45 May cause cancer 可能致癌
- R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- P403+P235
- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P370+P378
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- P301+P330+
- P301+P312+P330
- P304+P340+P310
- P308+P313
- P403+P233
- P305+P351+P338+P310
- H332 Harmful if inhaled 吸入有害
- H315 Causes skin irritation 会刺激皮肤
- H302 Harmful if swallowed 吞食有害
- H312 Harmful in contact with skin 皮肤接触有害
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- H350 May cause cancer 可能致癌
- H340 May cause genetic defects 可能导致遗传性缺陷
- H319 Causes serious eye irritation 严重刺激眼睛
- H224 Extremely flammable liquid and vapour 极端易燃液体和蒸气
- H302+H312+H332
- H331 Toxic if inhaled 吸入中毒
- H302+H312
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 272 mg/kg/95W-I TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Blood - lymphoma, including Hodgkin's disease Tumorigenic - tumors at site of application REFERENCE : ZHPMAT Zentralblatt fuer Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene, Abteilung 1: Originale, Reihe B: Hygiene, Krankenhaushygiene, Betriebshygiene, Praeventive Medizin. (Stuttgart, Fed. Rep. Ger.) V.155-169, 1971-1979. For publisher information, see ZAOMDC. Volume(issue)/page/year: 174,383,1981
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 10798 mg/kg/2Y-I TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors REFERENCE : BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 46,924,1982
TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 100 ppm/7H/2Y-I TOXIC EFFECTS : Tumorigenic - neoplastic by RTECS criteria Endocrine
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1500 mg/kg/46W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - facilitates action of known carcinogen REFERENCE : ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 68,750,1958
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 150 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,103,1982
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1740 ppm/4H TOXIC EFFECTS : Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - changes in structure or function of salivary glands REFERENCE : AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 13,237,1956
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 4000 ppm/4H TOXIC EFFECTS : Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Sense Organs and Special Senses (Eye) - lacrimation Lungs, Thorax, or Respiration - dyspnea REFERENCE : AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 13,237,1956
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 660 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Liver - other changes Kidney, Ureter, Bl
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 700 ug/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/yea
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Klebsiella pneumoniae DOSE/DURATION : 500 umol/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 89,269,1981
TYPE OF TEST : Specific locus test TEST SYSTEM : Rodent - mouse Lymphocyte DOSE/DURATION : 160 ppm/48H (Continuous) REFERENCE : EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 17,122,1991
TYPE OF TEST : Sex chromosome loss and nondisjunction ROUTE OF EXPOSURE : Parenteral TEST SYSTEM : Insect - Drosophila melanogaster DOSE/DURATION : 10 ppb REFERENCE : EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Lis
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Yeast - Schizosaccharomyces pombe DOSE/DURATION : 183 mmol/L REFERENCE : ADWMAX Abhandlungen der Deutschen Akademie der Wissenschaften zu Berlin, Klasse fuer Medizin. (Berlin, Ger. Dem. Rep.) 1950-68. Discontinued. Volume(issue)/page/year: -,193,1962
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 700 ug/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 67,101,1979
TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE : 500 ppm/7H SEX/DURATION : female 7-16 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghous
TYPE OF
TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Primate - monkey DOSE : 100 ppm/7H SEX/DURATION : male 2 year(s) pre-mating TOXIC EFFECTS : Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) REFERENCE : TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 3,60,1983
TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE : 500 ppm/7H SEX/DURATION : female 15 day(s) pre-mating
TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE : 500 ppm/7H SEX/DURATION : female 1-16 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB83-258038
其他信息
- 能与乙醇、乙醚混溶,与水部分混溶,水中溶解度:40g/100ml (20°C),并与二氯甲烷、戊烷、戊烯、环戊烷、环戊烯等形成二元共沸物。