(S)-4-Aminohex-5-Enoic Acid (S)-氨己烯酸
CAS 74046-07-4 MFCD00274076
化学结构图
SMILES: C=C[C@@H](N)CCC(O)=O
化学属性
| Mol. Formula | C6H11NO2 |
|---|---|
| Mol. Weight | 129.16 |
别名和识别编码
| Chemical Name | (S)-4-Aminohex-5-Enoic Acid |
|---|---|
| CAS Number | 74046-07-4 |
| Synonym | (4S)- S(+)-γ-Vigabatrin S(+)-γ-Vinyl GABA S(+)-γ-Vinyl GABA S(+)-4-Aminohexenoic acid S(+)-4-Aminohexenoic acid |
| MDL Number | MFCD00274076 |
| PubChem Substance ID | 24900710 |
| Chemical Name Translation | (S)-氨己烯酸 |
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分类
- Chiral Reagents
- Pharmaceuticals
- {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, GABA-Transaminase, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, V
- Intermediates & Fine Chemicals
- {SNA} Bioactive Small Molecule Alphabetical Index, Enzyme Inhibitors, GABA-Transaminase, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, V, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- Amines
产品应用
- A novel antiepileptic
相关文献及参考
- Vajda, F., et al.: Clin. Neurosci., 7, 88 (2000),
- Beghi, E., et al.: Lancet. Neurol., 3, 618 (2004),
- Sagirli, O., et al.: J. Pharmaceut. Biomed., 42, 618 (2006),
- Larsson, et al., Differential effect of gamma-vinyl GABA and valproate on GABA-transaminase from cultured neurons and astrocytes. Neuropharmacology 25 , 617-625, (1986) 摘要
- Robin, et al., An analysis of the cortical and striatal involvement in dyskinesia induced in rats by intracerebral injection of GABA-transaminase inhibitors and picrotoxin. Eur. J. Pharmacol. 62 , 319, (1980) 摘要
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
