N-Cyclohexyl-N-Methyl-4-((2-Oxo-1,2-Dihydroquinolin-6-Yl)Oxy)Butanamide N-环己基-N-甲基-4-((2-氧代-1,2-二氢喹啉-6-基)氧基)丁酰胺
CAS 68550-75-4 MFCD00673958
化学结构图
SMILES: CN(C1CCCCC1)C(=O)CCCOC1=CC2C=CC(=O)NC=2C=C1
化学属性
| Mol. Formula | C20H26N2O3 |
|---|---|
| Mol. Weight | 342.43 |
| TSCA | No |
别名和识别编码
| Chemical Name | N-Cyclohexyl-N-Methyl-4-((2-Oxo-1,2-Dihydroquinolin-6-Yl)Oxy)Butanamide |
|---|---|
| Synonym | 6-[3-(N-Cyclohexyl-N-methylcarbamoyl)propoxy]quinolin-2[1H]-one 6-[3-(N-Cyclohexyl-N-methylcarbamoyl)propoxy]quinolin-2[1H]-one OPC 3689 OPC 3689 |
| MDL Number | MFCD00673958 |
| PubChem Substance ID | 24278337 |
| CAS Number | 68550-75-4 |
| Chemical Name Translation | N-环己基-N-甲基-4-((2-氧代-1,2-二氢喹啉-6-基)氧基)丁酰胺 |
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分类
- {SNA} Cyclic Nucleotide Metabolism, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, G Proteins and Cyclic Nucleotides, P to Q, Phosphodiesterase III, Phosphodiesterase Inhibitors, 生化试剂, 细胞信号转导和神经科学, 细胞生物学, 酶、抑制剂和底物
- {SNA} Bioactive Small Molecules, Biochemicals and Reagents, CI-CY, Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, G Proteins and Cyclic Nucleotides,
- {SA} Bioactive Small Molecules, Biochemicals and Reagents, CI-CY, Cell B
相关文献及参考
- 1. Hayashi, H., and Sudo, T., Effects of the cAMP-elevating agents cilostamide, cilostazol and forskolin on the phosphorylation of Akt and GSK-3beta in platelets Thromb. Haemost. 102 , 327-335, (2009) 摘要
- Tang, K.M., et al. Eur. J. Pharmacol. 268 , 105, (1994) 摘要
- Verghase, M.W., et al. J. Pharmacol. Exp. Ther. 272 , 1313, (1995) 摘要
- [1]. Sudo T, et al. Potent effects of novel anti-platelet aggregatory cilostamide analogues on recombinant cyclic nucleotide phosphodiesterase isozyme activity. Biochem Pharmacol. 2000 Feb 15;59(4):347-56.
