5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-[2-(METHYLPHENYLAMINO)ETHENYL]-1-PHENYL-1H-BENZIMIDAZOLIUM IODIDE
CAS 681281-88-9 MFCD00570739
化学结构图
SMILES: [I-].CN(/C=C/C1N(C2C=CC(=CC=2[N+]=1CC)C1=NC2C=CC=CC=2S1)C1C=CC=CC=1)C1C=CC=CC=1
化学属性
| Mol. Formula | C31H27IN4S |
|---|---|
| Mol. Weight | 614.54 |
别名和识别编码
| Chemical Name | 5-(2-Benzothiazolyl)-3-ethyl-2-[2-(methylphenylamino)ethenyl]-1-phenyl-1H-benzimidazolium iodide |
|---|---|
| MDL Number | MFCD00570739 |
| PubChem Substance ID | 24724416 |
| CAS Number | 681281-88-9 |
| Chemical Name Translation | |
| Synonym |
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分类
- {SNA} B, Bioactive Small Molecule Alphabetical Index, Kinase/Phosphatase Biology, Protein Kinase B (Akt/PKB), Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- B, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Protein Kinase B (Akt/PKB), Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors
相关文献及参考
- Chautard, E., et al., Akt Signaling Pathway: A Target For Radiosensitizing Human Malignant Glioma. Neuro-Oncol. 12 , 434-43, (2010) 摘要
- Chavali, P.L., et al., Nuclear Orphan Receptor TLX Induces Oct-3/4 For The Survival And Maintenance Of Adult Hippocampal Progenitors Upon Hypoxia. J. Thorac. Cardiovasc. Surg. 286 , 9393-404, (2011) 摘要
- Kau, T.R., et al. , A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells. Cancer Cell 4 , 463-476, (2003) 摘要
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
