Sodium arachidonate 花生四烯酸 钠盐
CAS 6610-25-9 MFCD00065458
化学结构图
SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)[O-].[Na+]
化学属性
| Mol. Formula | C20H31O2Na |
|---|---|
| Mol. Weight | 326.45 |
别名和识别编码
| Chemical Name | 5,8,11,14-Eicosatetraenoic acid, sodium salt, (all-Z)- |
|---|---|
| Synonym | (all-Z)-5,8,11,14-Eicosatetraenoic acid 5,8,11,14-二十碳四烯酸 5,8,11,14-二十碳四烯酸 二十碳-5Z,8Z,11Z,14Z-四烯酸 花生四烯酸钠 顺,顺,顺,顺-5,8,11,14-二十碳四烯酸钠，20:4 Arachidonate, Sodium Arachidonic Acid Arachidonic Acid, (all-Z)-Isomer, 1-(14)C-Labeled Arachidonic Acid, (all-Z)-isomer, 3H-Labeled Arachidonic Acid, Ammonium Salt, (all-Z)-Isomer Arachidonic Acid, Cerium Salt, (all-Z)-Isomer Arachidonic Acid, Cesium Salt, (all-Z)-Isomer Arachidonic Acid, Lithium Salt, (all-Z)-Isomer Arachidonic Acid, Potassium Salt, (all-Z)-Isomer Arachidonic Acid, Sodium Salt Arachidonic Acid, Sodium Salt, (all-Z)-Isomer Arachidonic Acid, Zinc Salt, (all-Z)-Isomer Arachidonic acid sodium salt Sodium Arachidonate Sodium arachidonate Vitamin F 二十碳-5Z,8Z,11Z,14Z-四烯酸 花生四烯酸 钠盐 花生四烯酸钠 顺,顺,顺,顺 |
| MDL Number | MFCD00065458 |
| PubChem Substance ID | 23675453 |
| CAS Number | 6610-25-9 |
| Chemical Name Translation | 花生四烯酸 钠盐 |
| InChIKey | DDMGAAYEUNWXSI-XVSDJDOKSA-M |
| InChI | InChI=1S/C20H32O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22;/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22);/q;+1/p-1/b7-6-,10-9-,13-12-,16-15-; |
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资金保障
专业采购外包团队在线服务
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分类
- {SNA} Fatty Acids and conjugates,
- {SNA} AN-AZ, Arachidonic Acid, Arachidonic Acid Cascade, Bioactive Small Molecules, Biochemicals and Reagents,
- {SNA} AN-AZ, Arachidonic Acid, Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, Fatty Acids and conjugates, Fatty Acyls, Functional Foods, Lipids, Lipids in Cell Signaling, Omega 6 fatty acids and derivatives, Polyunsaturated, Polyunsaturated Fatty Acids (PUFAs) and Omega-3 Fatty Acids, Unsaturated Fatty Acids and Derivatives, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 脂类, 营养研究
相关文献及参考
- Ghosh, J., and Myers, C.E., Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells. Proc. Natl. Acad. Sci. U. S. A. 95 , 13182-13187, (1998) 摘要
- Prigge, S.T., et al., Structure and mechanism of lipoxygenases. Biochimie 79 , 629-636, (1997)
- Karim, S., et al., Cyclooxygenase-1 and -2 of endothelial cells utilize exogenous or endogenous arachidonic acid for transcellular production of thromboxane. J. Biol. Chem. 271 , 12042-12048, (1996)
- Krischer, S.M., et al., Transport of arachidonic acid across the neutrophil plasma membrane via a protein-facilitated mechanism. Biochemistry 37 , 12884-12891, (1998) 摘要
- Makita, K., et al., Cytochrome P450, the arachidonic acid cascade, and hypertension: new vistas for an old enzyme system. FASEB J. 10 , 1456-1463, (1996)
- Kim, B.C, and Kim, J.H.,, Nuclear signalling by Rac GTPase: essential role of phospholipase A2. Biochem. J. 326 , 333-337, (1997)
- Seegers, J.C., et al., Comparative anti-mitotic effects of lithium γ-linolenate, γ-linolenic acid and arachidonic acid, on transformed and embryonic cells. Prostaglandins Leukot. Essent. Fatty Acids 59 , 285-291, (1998) 摘要
- Williams, J.R., et al., Apoptosis in human primary brain tumours: actions of arachidonic acid. Prostaglandins Leukot. Essent. Fatty Acids 58 , 193-200, (1998)
- Hallak, H., et al., Covalent binding of arachidonate to G protein alpha subunits of human platelets. J. Biol. Chem. 269 , 4713-4716, (1994) 摘要
- Sermon, B.A., et al., Mechanism of inhibition by arachidonic acid of the catalytic activity of Ras GTPase-activating proteins. J. Biol. Chem. 271 , 1566-1572, (1996) 摘要
安全信息
- R19 May form explosive peroxides 可能生成易爆的过氧化物质
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 33 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - other changes REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 224,369,1983
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 1 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - respiratory obstruction Lungs, Thorax, or Respiration - cyanosis REFERENCE : THBRAA Thrombosis Research. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1972- Volume(issue)/page/year: 9,67,1976
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - respiratory obstruction Lungs, Thorax, or Respiration - cyanosis REFERENCE : THBRAA Thrombosis Research. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1972- Volume(issue)/page/year: 9,67,1976
