S-(+)-N-去甲基美芬妥英 S-(+)-N-去甲基美芬妥英
CAS 65567-34-2 MFCD00272652
化学结构图
SMILES: CC[C@]1(NC(=O)NC1=O)C1C=CC=CC=1
化学属性
| Mol. Formula | C11H12N2O2 |
|---|---|
| Mol. Weight | 204.23 |
别名和识别编码
| Chemical Name | (S)-(+)-Nirvanol |
|---|---|
| CAS Number | 65567-34-2 |
| Synonym | (+)-5-Ethyl-5-phenylhydantoin (+)-Nirvanol (S)-(+)-5-Ethyl-5-phenyl-2,4-imidazolidinedione (S)-(+)-5-Ethyl-5-phenyl-2,4-imidazolidinedione (S)-(+)-5-Ethyl-5-phenylhydantoin (S)-(+)-5-Ethyl-5-phenylhydantoin (S)-(+)-Nirvanol (S)-5-Ethyl-5-phenyl-2,4-imidazolidinedione (S)-Nirvanol 2,4-Imidazolidinedione, 5-ethyl-5-phenyl-, (S)- S-(+)-Nirvanol, S-(+)-5-Ethyl-5-phenylhydantoin |
| MDL Number | MFCD00272652 |
| Chemical Name Translation | S-(+)-N-去甲基美芬妥英 |
| Beilstein Registry Number | 0085311 |
| PubChem Substance ID | 329827656 |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- Pharmaceuticals
- {SNA} Bioactive Small Molecule Alphabetical Index, Drug and Xenobiotic Metabolism, Multi-Drug Resistance and Drug Metabolism, N, Substrates, Inducers, Inhibitors, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- Heterocycles
- {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Drug and Xenobiotic Metabolism, Multi-Drug Resistance and Drug Metabolism, N, Substrates, Inducers, Inhibitors
- Hydantoins & Derivatives
- Intermediates & Fine Chemicals,
- Metabolites & Impurities
产品应用
- An anticonvulsant, hypnotic. A metabolite of Mephentoin.
相关文献及参考
- Knabe, J., et al.: Arch. Phar., 313, 538 (1980)
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- H302 Harmful if swallowed 吞食有害
- H319 Causes serious eye irritation 严重刺激眼睛
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R22 Harmful if swallowed 吞咽有害
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - child DOSE/DURATION : 140 mg/kg TOXIC EFFECTS : Skin and Appendages - dermatitis, allergic (after systemic exposure) Nutritional and Gross Metabolic - body temperature increase REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 47,209,1933
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BBIADT Biomedica Biochimica Acta. (Akademie-Verlag GmbH, Postfach 1233, Berlin DDR-1086, Ger. Dem. Rep.) V.42- 1983- Volume(issue)/page/year: 46,623,1987
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 47,209,1933
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 175 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 47
