5-((Methyl(prop-2-yn-1-yl)amino)methyl)quinolin-8-ol dihydrochloride 5-((甲基(丙-2-炔-1-基)氨基)甲基)喹啉-8-醇二盐酸盐
CAS 64821-19-8 MFCD20488063
化学结构图
SMILES:
化学属性
| Mol. Weight | 299.20 |
|---|---|
| Mol. Formula | C14H14N2O · 2HCl |
别名和识别编码
| Synonym | 5-[N-methyl-N-propargylaminomethyl]-8-hydroxyquinoline dihydrochloride 5-[N-methyl-N-propargylaminomethyl]-8-hydroxyquinoline dihydrochloride M-30 dihydrochloride VAR10300 dihydrochloride M-30 dihydrochloride M30 dihydrochloride VAR10300 dihydrochloride |
|---|---|
| MDL Number | MFCD20488063 |
| CAS Number | 64821-19-8 |
| Chemical Name | 5-((Methyl(prop-2-yn-1-yl)amino)methyl)quinolin-8-ol dihydrochloride |
| PubChem Substance ID | 329825178 |
| Chemical Name Translation | 5-((甲基(丙-2-炔-1-基)氨基)甲基)喹啉-8-醇二盐酸盐 |
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分类
- {SNA} Bioactive Small Molecule Alphabetical Index, Enzyme Inhibitors, M, Monoamine Oxidase, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, M, Monoamine Oxidase, Neuroscience, Neurotransmission, Neurotransmitter Metabolism
相关文献及参考
- Kupershmidt L, Weinreb O, Amit T, Mandel S, Carri MT, Youdim MB., Neuroprotective and neuritogenic activities of novel multimodal iron-chelating drugs in motor-neuron-like NSC-34 cells and transgenic mouse model of amyotrophic lateral sclerosis. FASEB J. 23 , 3766-3779, (2009)
- Mechlovich D, Amit T, Mandel SA, Bar-Am O, Bloch K, Vardi P, Youdim MB., The novel multifunctional, iron-chelating drugs M30 and HLA20 protect pancreatic beta-cell lines from oxidative stress damage. J. Pharmacol. Exp. Ther. 333 , 874-882, (2010) 摘要
- Zheng H, Youdim MB, Fridkin M., Site-activated chelators targeting acetylcholinesterase and monoamine oxidase for Alzheimer's therapy. ACS Chem. Biol. 5 , 603-610, (2010) 摘要
安全信息
GHS Symbol
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- H318 Causes serious eye damage 严重伤害眼睛
- H302 Harmful if swallowed 吞食有害
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S39 Wear eye/face protection 戴眼睛/面孔保护装置；
- R22 Harmful if swallowed 吞咽有害
- R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
