CAS 64-72-2 MFCD00082440-Chlortetracycline Hydrochloride 盐酸金霉素 TAO{mole}

Chlortetracycline Hydrochloride 盐酸金霉素

CAS 64-72-2 MFCD00082440

化学结构图

SMILES: CN(C)C1C(=O)C(C(N)=O)=C(O)C2(O)C(=O)C3=C(O)c4c(O)ccc(Cl)c4C(C)(O)C3CC12.Cl

化学属性

Mol. Formula	C22H24Cl2N2O8
Mol. Weight	515
Melting Point	210-215
Stability	对光敏感
Density	1.177

别名和识别编码

Chemical Name	Chlortetracycline Hydrochloride
CAS Number	64-72-2
Synonym	######## 2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,monohydrochloride 6-甲基-4-(二甲氨基)-3,6,10,12,12a-五羟基-1,11-二氧代-7-氯-1,4,4a,5,5a,6,11,12a-八氢-2-并四苯甲酰胺盐酸盐 7-CHLOROTETRACYCLINE HYDROCHLORIDE 7-CHLORTETRACYCLINE MONOHYDROCHLORIDE AUREOMYCIN(TM) Aureociclina CHLOROTETRACYCLINE HCL CHLOROTETRACYCLINE HYDROCHLORIDE CTC Chlorotetracycline hydrochloride Chlortetracycline hydrochloride Clorotetraciclina cloridrato NSC-13252 chlortetracyclinehydrochloride’canbeusedassecondarystandard’ 氯四环素盐酸盐
PubChem Substance ID	54682468
EC Number	200-591-7
Beilstein Registry Number	3858364
MDL Number	MFCD00082440
Chemical Name Translation	盐酸金霉素
Merck Number	13,2211
Wiswesser Line Notation	L E6 C666 BV FV CU GUTTT&J DQ EQ GVZ HQ IN1&1 MQ M1OG RQ &GH
LabNetwork Molecule ID	LN00876908
InChI	InChI=1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26-27,30,32-33H,6H2,1-3H3,(H2,24,31);1H/t7-,8-,15-,21-,22-;/m0./s1

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

细胞渗透荧光探针，用于测量内质网Ca2+ 流量。

安全信息

GHS Symbol

WGK Germany2

Hazard Codes Xi

Hazard statements

H315 Causes skin irritation 会刺激皮肤
H319 Causes serious eye irritation 严重刺激眼睛
H335 May cause respiratory irritation 可能导致呼吸道刺激

RTECSQI7800000

Precautionary statements

P305+P351+P338

Signal word Warning

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

Safety Statements

S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；

Storage condition 2-8℃保存。遮光，密封 2-8°C

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ANYAA9 Annals of the New York Academy of Sciences.  (New York Academy of
   Sciences, 2 E. 63rd St., New York, NY 10021)  V.1-    1877-
   Volume(issue)/page/year: 51,182,1948

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Lungs, Thorax, or Respiration - dyspnea
   Kidney, Ureter, Bladder - hematuria
REFERENCE :
   ANYAA9 Annals of the New York Academy of Sciences.  (New York Academy of
   Sciences, 2 E. 63rd St., New York, NY 10021)  V.1-    1877-
   Volume(issue)/page/year: 51,254,1948

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : >50 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - nausea or vomiting
REFERENCE :
   ANYAA9 Annals of the New York Academy of Sciences.  (New York Academy of
   Sciences, 2 E. 63rd St., New York, NY 10021)  V.1-    1877-
   Volume(issue)/page/year: 51,182,1948

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 1125 mg/kg
SEX/DURATION            : female 10-18 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4
   per # born alive)
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 161,300,1967

其他信息

Sigma Aldrich:64-72-2(sigmaaldrich)
用途一:属广谱抗生素，对革兰阳性和阴性菌均有抗菌作用
盐酸金霉素价格(试剂级):更新日期产品编号产品名称包装价格 2010/06/21 430960050 盐酸金霉素 Chlortetracycline hydrochloride , conforms to Eur. Ph. 5 GR 473元 2010/06/21 430961000 盐酸金霉素 Chlortetracycline hydrochloride , conforms to Eur. Ph. 100 GR 3547元 2010/06/21 430960250 盐酸金霉素 Chlortetracycline hydrochloride , conforms to Eur. Ph. 25 GR 1253元
上游原料:盐酸 --> 淀粉 --> 酵母粉
MSDS 信息:[4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha)]-7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride(64-72-2).msds
用途三:细胞渗透荧光探针，用于测量内质网Ca2+ 流量。
MOL 文件:64-72-2.mol
Acros Organics:金霉素盐酸盐 Chlortetracycline hydrochloride, potency 900 ug/mg(64-72-2)
无臭，味苦；遇光色渐变暗。在水或乙醇中微溶，在丙酮、乙醚、二氧六环、丙二醇或氯仿中几乎不溶，溶于氢氧化物和碳酸盐碱溶液。溶解度:8.6 g/L 水(28°C)、17.4 g/L 甲醇(28°C), 1.7 g/L 乙醇(28°C)。
外观性质:金黄色或黄色结晶；无臭，味苦；遇光色渐变暗。在水或乙醇中微溶，在丙酮、乙醚、二氧六环、丙二醇或氯仿中几乎不溶，溶于氢氧化物和碳酸盐碱溶液。溶解度:8.6 g/L 水(28°C)、17.4 g/L 甲醇(28°C), 1.7 g/L 乙醇(28°C)。熔点：220℃ 比旋度为-235°至-250°
用途二:广谱抗生素，对革兰氏阳性和阴性菌均有抗菌作用。