Vicriviroc Maleate
CAS 599179-03-0 MFCD11973900
化学结构图
SMILES: CC1(CCN(CC1)C(=O)C1C(C)=NC=NC=1C)N1CCN([C@@H](COC)C2C=CC(=CC=2)C(F)(F)F)[C@@H](C)C1.OC(=O)/C=C/C(O)=O
化学属性
| Mol. Formula | C28H38F3N5O2 |
|---|---|
| Mol. Weight | 534 |
别名和识别编码
| Chemical Name | Vicriviroc Maleate |
|---|---|
| Chemical Name Translation | |
| MDL Number | |
| CAS Number | 599179-03-0 |
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相关文献及参考
- [2]. Strizki JM, et al. Discovery and characterization of vicriviroc (SCH 417690), a CCR5 antagonist with potent activity against human immunodeficiency virus type 1. Antimicrob Agents Chemother. 2005 Dec;49(12):4911-9.
- [1]. Tagat JR, et al. Piperazine-based CCR5 antagonists as HIV-1 inhibitors. IV. Discovery of 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]- 4-[4-[2-methoxy-1(R)-4-(trifluoromethyl)phenyl]ethyl-3(S)-methyl-1-piperazinyl]- 4-methylpiperidine (Sch-417690/Sch-D), a potent, highly selective, and orally bioavailable CCR5 antagonist. J Med Chem. 2004 May 6;47(10):2405-8.
- [1]. Tagat JR, et al. Piperazine-based CCR5 antagonists as HIV-1 inhibitors. IV. Discovery of 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]- 4-[4-[2-methoxy-1(R)-4-(trifluoromethyl)phenyl]ethyl-3(S)-methyl-1-piperazinyl]- 4-methylpiperidine (Sch-417690/Sch-D), a potent, highly selective, and orally bioavailable CCR5 antagonist. J Med Chem. 2004 May 6;47(10):2405-8.
- [2]. Strizki JM, et a
