CAS 59456-70-1 MFCD00869648-beta-D-Allofuranuronic acid,5-((2-amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-3-methyl-1-oxobutyl)amino)-1,5-dideoxy-1-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-, (2S-(2R*,3R*,4R*))- TAO{mole}

beta-D-Allofuranuronic acid,5-((2-amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-3-methyl-1-oxobutyl)amino)-1,5-dideoxy-1-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-, (2S-(2R,3R,4R*))-

CAS 59456-70-1 MFCD00869648

化学结构图

SMILES: C[C@@H]([C@H](N)C(=O)N[C@H]([C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=O)NC1=O)C(O)=O)[C@H](O)C1C=CC(O)=CN=1

化学属性

Mol. Formula	C20H25N5O10
Mol. Weight	495.44

别名和识别编码

Chemical Name	Nikkomycin Z from Streptomyces tendae
MDL Number	MFCD00869648
PubChem Substance ID	24897849
Beilstein Registry Number	0873216
Synonym	Nikkomycin Z Neopolyoxin C Nikkomycin Z from Streptomyces tendae
CAS Number	59456-70-1

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分类

{SA} Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antifungal, Chemical Structure Class, Inhibits an Enzyme, Interferes with Cell Wall Synthesis, Mechanism of Action, Peptidyl Nucleosides, Spectrum of Activity
{SNA} Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antifungal, Chemical Structure Class, Glycobiology, Inhibitors, Inhibitors and Substrates, Inhibits an Enzyme, Interferes with Cell Wall Synthesis, Mechanism of Action, Peptidyl Nucleosides, Post-Translational Modification, Proteomics, Spectrum of Activity
{SNA} Antibiotics

安全信息

WGK Germany3

GHS Symbol

Precautionary statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P305+P351+P338

Hazard statements

H315 Causes skin irritation 会刺激皮肤
H319 Causes serious eye irritation 严重刺激眼睛
H335 May cause respiratory irritation 可能导致呼吸道刺激

RTECSBA2928200

Signal word Warning

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes Xi

Safety Statements

S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S36 Wear suitable protective clothing 穿戴适当的防护服；

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ABCHA6 Agricultural and Biological Chemistry.  (Maruzen Co. Ltd., POB 5050,
   Tokyo International, Tokyo 100-31, Japan)  V.25-    1961-
   Volume(issue)/page/year: 44,1709,1980