CAS 58880-19-6 MFCD03848392-Trichostatin A 曲古抑菌素 A TAO{mole}

Trichostatin A 曲古抑菌素 A

CAS 58880-19-6 MFCD03848392

化学结构图

SMILES: C/C(/C=C/C(=O)NO)=C\[C@@H](C)C(=O)C1C=CC(=CC=1)N(C)C

化学属性

Mol. Formula	C17
Mol. Weight	302

别名和识别编码

Chemical Name	Trichostatin A
Synonym	TSA TSA [R-(E,E)]-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide Trichostatin A Trichostatin A, Ready Made Solution [R-(E,E)]-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
CAS Number	58880-19-6
Reaxys-RN	2391788
PubChem Substance ID	87560260
MDL Number	MFCD03848392
Merck Number	9649
Chemical Name Translation	曲古抑菌素 A

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分类

{SNA} Antitumor Agents, Bioactive Small Molecules, Bioactive Small Molecules for Epigenetic Research, Biochemicals and Reagents, Cancer Research, Cell Biology, Cell Signaling and Neuroscience, D to K, DNA-RNA Transcription Regulators, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Epigenetics, Gene Regulation and Expression, Histone Deacetylase Inhibitors, Histone deacetylase, Hydroxamic Acid Inhibitors, Molecular Biology, Reagents, Small Molecules for Stem Cell Biology, Stem Cell Biology, T, Tools for Gene Regulation Research
{SNA} Antibiotic Ready Made Sol
{SNA} Antibiotic Ready Made Solutions,

安全信息

WGK Germany3

Personal Protective Equipment Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US) dust mask type N95 (US), Eyeshields, Faceshields, Gloves

RTECSMI5215000

Storage condition <;0 <0°C

Signal word

Hazard statements

H332 Harmful if inhaled 吸入有害
H315 Causes skin irritation 会刺激皮肤
H317 May cause an allergic skin reaction 可能导致皮肤过敏
H302 Harmful if swallowed 吞食有害
H312 Harmful in contact with skin 皮肤接触有害
H335 May cause respiratory irritation 可能导致呼吸道刺激
H319 Causes serious eye irritation 严重刺激眼睛
H302+H312+H332

Precautionary statements

P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P304+P340+P312
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
P332+P313
P302+P352+P312+P362+P364
P501 Dispose of contents/container to..… 处理内容物/容器.....
P305+P351+P338+

GHS Symbol

Hazard Codes Xn

Safety Statements

S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S36 Wear suitable protective clothing 穿戴适当的防护服；

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - rat Embryo
DOSE/DURATION           : 100 ug/L
REFERENCE :
   ECREAL Experimental Cell Research.  (Academic Press, Inc., 1 E. First St.,
   Duluth, MN 55802) V.10-    1950-  Volume(issue)/page/year: 177,122,1988

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Rodent - rat Embryo
DOSE/DURATION           : 100 ug/L
REFERENCE :
   ECREAL Experimental Cell Research.  (Academic Press, Inc., 1 E. First St.,
   Duluth, MN 55802) V.10-    1950-  Volume(issue)/page/year: 177,122,1988

Trichostatin A 曲古抑菌素 A

CAS 58880-19-6 MFCD03848392

化学结构图

化学属性

别名和识别编码

分类

相关文献及参考

安全信息

系列性分类

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