8-Aminoquinoline 8-氨基喹啉

CAS 578-66-5 MFCD00006809

化学结构图

578-66-5
SMILES: Nc1cccc2cccnc12

化学属性

Mol. FormulaC9H8N2
Mol. Weight144.17
Boiling Point289.8°C at 760 mmHg
Melting Point62-65°C
Density1.21
TSCAYes
Solubility不溶于水,溶于乙醇、丙酮、汽油、苯。
Stability对空气敏感
Flash Point174°C/26mm

别名和识别编码

Chemical Name8-Aminoquinoline
CAS Number578-66-5
Alfabeta NameAMINOQUINOLINE 8-
MDL NumberMFCD00006809
Synonym 8-Aminoquinoline {LY} 8-Aminoquinoline {} {LY} 8-Aminoquinoline {} {} {LY} 8-Aminoquinoline {} {} {} {LY} 8-Aminoquinoline {} {} {} {} {LY} 8-Aminoquinoline {} {} {} {} {} {LY} 8-Aminoquinoline {} {} {} {} {} {} {LY} 8-Aminoquinoline {} {} {} {} {} {} {} {LY} 8-Aminoquinoline {} {} {} {} {} {} {} {} {LY} 8-Aminoquinoline {} {} {} {} {} {} {} {} {} {LY} 8-Aminoquinoline {} {} {} {} {} {} {} {} {} {} {LY} 8-Aminoquinoline {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {LY} 8-Aminoquinoline {} {} {} {} {} {} {} {} {} {} {} {} {LY} 8-Aminoquinoline {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 8-Aminoquinoline {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 8-Aminoquinoline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 8-Aminoquinoline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 8-Aminoquinoline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {}
PubChem Substance ID11359
EC Number209-427-9
Beilstein Registry Number114474
Chemical Name Translation8-氨基喹啉
Reaxys-RN114474
Wiswesser Line NotationT66 BNJ JQ
LabNetwork Molecule IDLN00119134
InChIInChI=1S/C9H8N2/c10-8-5-1-3-7-4-2-6-11-9(7)8/h1-6H,10H2
Canonical SMILESNC1=C2N=CC=CC2=CC=C1
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分类

  • Building Blocks, C8 to C10, Chemical Synthesis, Heterocyclic Building Blocks, Quinolines
  • {SNA} Building Blocks, C8 to C10, Chemical Synthesis, Heterocyclic Building Blocks, Quinolines

产品应用

  • 用作医药中间体。

相关文献及参考

  • Beilstein:22(3/4)4708

安全信息

Warnings IRRITANT
GHS Symbol
WGK Germany3
Hazard Codes Xn,Xi Xi
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
RTECSVA9627000
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P350
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
Signal word Warning
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Risk Statements
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
  • R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
Storage condition 2-8°C, protect from light {LY} 2-8°C, protect from light {} {LY} 2-8°C, protect from light {} {} {LY} 2-8°C, protect from light {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 1 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 39,285,1977

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 50 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 39,285,1977

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 350 ug/disc
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 39,285,1977

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Leukocyte
DOSE/DURATION           : 100 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 39,285,1977

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 480 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - other effects
REFERENCE :
   TOXID9 Toxicologist.  (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway,
   Akron, OH 44311) V.1-    1981-  Volume(issue)/page/year: 3,65,1983

其他信息

  • 8-氨基喹啉价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 A0419 8-氨基喹啉 8-Aminoquinoline 25G 1350元 2014/06/02 A0419 8-氨基喹啉 8-Aminoquinoline 5G 479元 2010/06/21 123710050 8-氨基喹啉 8-Aminoquinoline 98+% 5 GR 506元
  • Sigma Aldrich:578-66-5(sigmaaldrich)
  • 下游产品:喹啉-8-硼酸 --> 1,10-菲罗啉
  • Alfa Aesar:8-氨基喹啉,98+% 8-Aminoquinoline, 98+%(578-66-5)
  • 海关编码:29334990
  • 用途一:用作医药中间体
  • 类别:有毒物品
  • MOL 文件:578-66-5.mol
  • 储运特性:库房通风低温干燥
  • 图谱信息:8-氨基喹啉(578-66-5)核磁图( 13 CNMR) 8-氨基喹啉(578-66-5)红外图谱(IR2) 8-氨基喹啉(578-66-5)红外图谱(IR1) 8-氨基喹啉(578-66-5)质谱(MS) 8-氨基喹啉(578-66-5)红外图谱(IR3)
  • 外观性质:黄色针状结晶。
  • 存储注意事项:氮气保护
  • 微溶于水。
  • 敏感性:Air Sensitive
  • MSDS 信息:8-氨基喹啉(578-66-5).msds
  • Acros Organics:8-氨基喹啉 8-Aminoquinoline, 98+%(578-66-5)
  • TCI Shanghai:8-氨基喹啉 8-Aminoquinoline,>;98.0%(T)(578-66-5)
  • 灭火剂:干粉、泡沫、砂土、二氧化碳, 雾状水
  • 可燃性危险特性:可燃;燃烧产生有毒氮氧化物烟雾
  • Hazard Note:Harmful/Irritant/Air Sensitive

系列性分类


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