3-Chloro-2-methylpropene 3-氯-2-甲基丙烯
CAS 563-47-3 MFCD00000953
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {Chemicalbook} 农药中间体: 杀螨剂中间体
- {uni_hamburg} no charge; 1fragment
- {SNA} Alkenyl, Building Blocks, Chemical Synthesis, Halogenated Hydrocarbons, Organic Building Blocks
产品应用
- 用作杀虫剂、塑料、药品等的中间体。
相关文献及参考
- Short: II/25C
- Short: III/20a
- Merck:14,2148
- Merck:14,2148 Beilstein:1,209
安全信息
GHS Symbol
- S9 Keep container in a well-ventilated place 保持容器在通风良好的场所;
- S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S29 Do not empty into drains 不要排入下水道;
- S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R34 Causes burns 会导致灼伤
- R51/53
- R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
- R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
- R11 Highly flammable 非常易燃
- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P233 Keep container tightly closed. ?保持容器密闭。
- P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
- P241+P242+P243
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
- P273 Avoid release to the environment. 避免释放到环境中。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P330+P331+P310
- P303+P361+P353
- P303+P361+P353+P310+P363
- P304+P340+P310
- P305+P351+P338
- P305+P351+P338+P310
- P308+P311
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P370+P378
- P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
- P403+P233
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
- H302 Harmful if swallowed 吞食有害
- H302+H332
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
- H317 May cause an allergic skin reaction 可能导致皮肤过敏
- H332 Harmful if inhaled 吸入有害
- H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 77250 mg/kg/2Y-I TOXIC EFFECTS : Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors Reproductive - Tumorigenic effects - testicular tumors REFERENCE : NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-300,1986
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 51500 mg/kg/2Y-I TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors REFERENCE : NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-300,1986
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 38625 mg/kg/2Y-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors REFERENCE : PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 26,95,1985
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 51500 mg/kg/2Y-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors REFERENCE : PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 26,95,1985
TYPE OF TES
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3160 mg/kg TOXIC EFFECTS : Gastrointestinal - other changes Liver - other changes Blood - changes in spleen REFERENCE : NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-300,1986
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 34 gm/m3/30M TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FAVUAI Fiziologicheski Aktivnye Veshchestva. Physiologically Active Substances. (Izdatel'stvo Naukova Dumka, Kiev, USSR) No.1- 1966- Volume(issue)/page/year: 7,35,1975
TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Human DOSE/DURATION : 22000 ppm/10M TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,377,1969
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 848 mg/kg TOXIC EFFECTS : Behavioral - tremor Gastrointestinal - hypermotility, diarrhea Blood - hemorrhage REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0539687
TYPE OF TEST : Mutation in mammalian somatic cells TEST SYSTEM : Rodent - mouse Lymphocyte DOSE/DURATION : 23200 ug/L REFERENCE : SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 236,933,1987
TYPE OF TEST : Sex chromosome loss and nondisjunction ROUTE OF EXPOSURE : Oral TEST SYSTEM : Insect - Drosophila melanogaster DOSE/DURATION : 4500 ppm REFERENCE : EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 23,208,1994
TYPE OF TEST : Unscheduled DNA synthesis TEST SYSTEM : Human HeLa cell DOSE/DURATION : 1 mmol/L REFERENCE : CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 20,263,1983
TYPE OF TEST : Sister chromatid exchange TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 16 mg/L REFERENCE : EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 13,133,1989
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 6 umol/plate REFERENCE : BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 29,2611,1980
TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 200 mg/L REFERENCE : NTPTR* National Toxicology Program Technical Report Series. (Research
其他信息
- Acros Organics:3-氯-2-甲基丙烯 3-Chloro-2-methylpropene, tech., 90%(563-47-3)
- {
- 上游原料:顺式十八碳-9-烯酸 --> 异丁烯
- 毒性分级:中毒
- 下游产品:克百威 --> 呋喃酚 --> 2,2,4,6,7-五甲基二氢苯并呋喃-5-磺酰氯 --> 2,2,4,6,7-五甲基苯并呋喃 --> 苯丁锡 --> 3-甲基-3-丁烯-1-醇 --> 双酚A二甲基丙烯酸酯 --> 邻(2-甲基烯丙氧基)苯酚 --> 1-氯-2-甲基-2-苯基丙烷 --> 甲基丙烯磺酸钠
- 急性毒性:口服-大鼠 LD50: 848 毫克/公斤; 口服-小鼠 LDL0: 3160 毫克/公斤
- 灭火剂:泡沫, 干粉, 二氧化碳, 砂土
- Alfa Aesar:3-氯-2-甲基丙烯,98% 3-Chloro-2-methylpropene, 98%(563-47-3)
- 用途一:用于合成杀螨锡、甲代烯丙基磺酸钠、3-氯-2-甲基环氧丙烷等
- 外观性质:无色或淡黄色易挥发的液体, 有刺激性气味。
- 用途二:2-甲基-3-氯丙烯又称甲代烯丙基氯,用于合成杀螨剂苯丁锡的中间体氯代叔丁基苯,也可用于合成杀虫剂克百威的中间体呋喃酚。
- Sigma Aldrich:563-47-3(sigmaaldrich)
- 蒸气密度:3.12 (vs air)
- 职业标准:STEL 0.3 毫克/立方米
- 用途三:该产品是一种重要的有机中间体,可广
- 类别:易燃液体
- 用途四:用作杀虫剂、塑料、药品等的中间体。
- 方法一:2-甲基-3-氯丙烯是由异丁烯与液氯反应制得。 异丁烯和液氯经气化后分别计量,然后按合适配比通入反应器,反应强烈放热,须严格控制反应接触时间,并在瞬间混合均匀进行反应。反应后物料进入反应蒸发器,移除反应热,再进入吸收冷凝器,将氯化氢吸收成盐酸,然后经冷却、油酸分离,盐酸可作为副产出售,有机层经分馏得到2-甲基-3-氯丙烯,含量可达95%~98%。
- 图谱信息:3-氯-2-甲基丙烯(563-47-3)核磁图( 1 HNMR) 3-氯-2-甲基丙烯(563-47-3)Raman光谱 3-氯-2-甲基丙烯(563-47-3)质谱(MS) 3-氯-2-甲基丙烯(563-47-3)红外图谱(IR1) 3-氯-2-甲基丙烯(563-47-3)核磁图( 13 CNMR)
- TCI Shanghai:3-氯-2-甲基-
- 可燃性危险特性:易燃; 受热分解有毒氯化物气体
- 3-氯-2-甲基丙烯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 C0209 3-氯-2-甲基-1-丙烯 3-Chlo
- MOL 文件:563-47-3.mol
- {Chemicalbo
- 有刺激性气味,微
- 爆炸物危险特性:与空气混合形成爆炸性混合物;
- 蒸气压:102 mm Hg ( 20 °C)
- MSDS 信息:1-氯-2-甲基-2-丙烯(563-47-3).msds
- 海关编码:29032900
- 用途三:该产品是一种重要的有机中间体,可广泛用于医药、农药、香料、合成材料等领域。
- 3-氯-2-甲基丙烯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 C0209 3-氯-2-甲基-1-丙烯 3-Chloro-2-methyl-1-propene 25ML 104元 2014/06/02 C0209 3-氯-2-甲基-1-丙烯 3-Chloro-2-methyl-1-propene 500ML 279元 2010/06/21 148420500 3-氯-2-甲基丙烯 3-Chloro-2-methylpropene 90%, tec