3-Aminomethyl-2,2,5,5-tetramethyl-1-pyrrolidinyloxy 3-(氨基甲基)-PROXYL
CAS 54606-49-4 MFCD00010547
化学结构图
SMILES: CC1(C)C(CN)CC(C)(C)N1[O] |^1:11|
化学属性
| Mol. Formula | C9H19N2O |
|---|---|
| Mol. Weight | 171.26 |
| Boiling Point | 128-131 °C/13 mmHg(lit.) |
别名和识别编码
| Chemical Name | 3-(Aminomethyl)-PROXYL |
|---|---|
| CAS Number | 54606-49-4 |
| Synonym | 3-(氨基甲基)-PROXYL 3-Aminomethyl-2,2,5,5-tetramethylpyrrolidine-N-oxyl 3-(氨基甲基)-2,2,5,5-四甲基-1-氧化吡咯烷 |
| MDL Number | MFCD00010547 |
| PubChem Substance ID | 24856359 |
| Chemical Name Translation | 3-(氨基甲基)-PROXYL |
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分类
- Nitric Oxide Reagents
- {SNA} Chemical Synthesis, Other Stable Radicals, Radical Chemistry, Stable Radicals, Synthetic Reagents
- Heterocycles
- {SA} Chemical Synthesis, Others, Radical Chemistry, Stable Radicals, Synthetic Reagents
相关文献及参考
- 1. S. Pou, A fluorophore-containing nitroxide as a probe to detect superoxide and hydroxyl radical generated by stimulated neutrophils. Anal. Biochem. 212 , 85, (1993)
- 2. Int. J. Pharm. 98 , 131, (1993)
- 3. X. Yang , Chasteen, N. D., Molecular diffusion into horse spleen ferritin: a nitroxide radical spin probe study. Biophys. J. 71 , 1587, (1996)
- 4. S. M. Hahn, Identification of nitroxide radioprotectors. Radiat. Res. 132 , 87, (1992)
- 5. S. M. Hahn, et al., In vivo radioprotection and effects on blood pressure of the stable free radical nitroxides Int. J. Radiation Oncology Biol. Phys. 42 , 839-842, (1998)
- 6. M. D. Rees, et al., Inhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxides Biochem. J. 421 , 79-86, (2009)
- 7. I. Kirilyuk, et al., Inclusion Complexes of Nitroxides of Pyrrolidine and Imidazoline Series with Cucurbit[7]uril J. Phys. Chem. B 114 , 1719-1728, (2010)
- 8. S. M. Devine, et al., Synthesis and evaluation of new N 6-substituted adenosine-5'-N-methylcarboxamides as A3 adenosine receptor agonists Bioorg. Med. Chem. 18 , 3078-3087, (2010)
- Aldrich MSDS 1 , 93:D / Corp MSDS 1 (1), 194:D / RegBook 1 (2), 2669:B / Sigma FT-IR 1 (2), 270:C / Structure Index 1 , 420:B:1
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- H319 Causes serious eye irritation 严重刺激眼睛
- H302+H312+H332
- H332 Harmful if inhaled 吸入有害
- H302 Harmful if swallowed 吞食有害
- H312 Harmful in contact with skin 皮肤接触有害
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
