Etonogestrel 依托孕烯
CAS 54048-10-1 MFCD00867863
化学结构图
SMILES: CC[C@]12CC(=C)[C@@H]3[C@H]4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@@]2(O)C#C
化学属性
| Mol. Formula | C22H28O2 |
|---|---|
| Mol. Weight | 324.46 |
别名和识别编码
| Chemical Name | Etonogestrel |
|---|---|
| CAS Number | 54048-10-1 |
| Synonym | (17-alpha)-13-Ethyl-17-hydroxy-11-methylene-18,19-dinorpregn-4-en-20-yn-3-one (17?)-13-Ethyl-17-hydroxy-11-methylene-18,19-dinorpregn-4-en-20-yn-3-one (17α)-13-Ethyl-17-hydroxy-11-methylene-18,19-dinorpregn-4-en-20-yn-3-one (17α)-13-Ethyl-17-hydroxy-11-methylene-18,19-dinorpregn-4-en-20-yn-3-one 3-Keto-desogestrel 3-Oxo-desogestrel 13-Ethyl-11-methylene-18,19-dinor-17-alpha-pregn-4-en-20-yn-3-one 17-Ethinyl-17-beta-hydroxy-18-methyl-11-methylene-4-estren-3-one 3-Keto-desogestrel 3-Ketodesogestrel 3-Oxo-desogestrel 3-Oxodesogestrel Implanon ORG 3236 Org-3236 |
| EC Number | 258-936-2 |
| Chemical Name Translation | 依托孕烯 |
| MDL Number | MFCD00867863 |
| PubChem Substance ID | 329825358 |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, New Products, Progesterone, Steroid Hormones
- {SNA} Bioactive Small Molecule Alphabetical Index, Cytokines, Growth Factors and Hormones, E, Hormones, Progesterone, Stero
产品应用
- A biologically active metabolite of Desogestrel.
相关文献及参考
- Croxatto, H.B., et al.: Hum. Reprod., 14, 976 (1999),
- Edwards, J.E., et al.: Brit. J. Fam. Plan., 24, 3 (1999),
- Krikun, G., et al., Effects of Etonogestrel Treatment in the Reproductive Organs and Uterine Arteries of Nonoophorectomized Guinea Pigs. Reprod. Sci. Jan 19 , (2012)
- Moser, C., et al., Simultaneous online SPE-LC-MS/MS quantification of six widely used synthetic progestins in human plasma. Anal. Bioanal. Chem Dec 10 , (2011)
- Lortlar, N., et al., The long-term effects of progesterone-only contraceptives on endometrium and ovary in rats. Arch. Pathol. 281 , 1051-1059, (2010)
安全信息
GHS Symbol
- P281 Use personal protective equipment as required. 使用所需的个人防护装备。
- P308+P313
- P201 Obtain special instructions before use. 使用前获取专门指示。
- H351 Suspected of causing cancer 怀疑致癌
- H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE : 50 ug/kg SEX/DURATION : female 1 day(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - other measures of fertility REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 35,459,1985
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - woman DOSE : 10500 ng/kg SEX/DURATION : female 21 day(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - other measures of fertility REFERENCE : CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 17,19,1978
- R60 May impair fertility 可能降低生殖能力
- R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
