Dyclonine hydrochloride 盐酸达克罗宁
CAS 536-43-6 MFCD00035386
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分类
- {SA} Alphabetic, Analytical Standards, Analytical/Chromatography, Chromatography, D, DJ - DZ, Drugs & Metabolites, Forensic and Veterinary Standards, Neat Compounds
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P310
- P301+P312+P330
- P302+P352+P332+P313+P362+P364
- P305+P351+P338
- P305+P351+P338+P310
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- H301 Toxic if swallowed 吞食有毒
- H302 Harmful if swallowed 吞食有害
- H315 Causes skin irritation 会刺激皮肤
- H318 Causes serious eye damage 严重伤害眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S36 Wear suitable protective clothing 穿戴适当的防护服;
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
- R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
- R22 Harmful if swallowed 吞咽有害
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 240 mg/kg TOXIC EFFECTS : Behavioral - ataxia REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,616,1960
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 9500 ug/kg TOXIC EFFECTS : Behavioral - tremor Gastrointestinal - changes in structure or function of salivary glands Gastrointestinal - nausea or vomiting REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 115,419,1955
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 37 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 201 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 115,413,1955
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE :
TYP
其他信息
- 图谱信息:盐酸达克罗宁(536-43-6)质谱(MS) 盐酸达克罗宁(536-43-6)红外图谱(IR2) 盐酸达克罗宁(536-43-6)红外图谱(IR1)
- Sigma Aldrich:536-43-6(sigmaaldrich)
- 储运特性:库房通风低温干燥
- 毒性分级:高毒
- 可燃性危险特性:热分解排出有毒氮氧化物, 氯化氢烟雾
- 灭火剂:水,干粉、干砂、二氧化碳、泡沫、1211灭火剂
- 上游原料:溴化钠
- 用途一:用于表面麻醉。
- Dyclonine HCl是Dyclonine的盐酸盐形式,是一种口服麻醉剂。
- 刺激数据:皮肤-兔 1% 轻度; 眼睛-兔 2% 重度
- 达克罗宁 盐酸盐
- MOL 文件:536-43-6.mol
- 急性毒性:腹腔-大鼠 LD50: 33 毫克/公斤; 腹腔-小鼠 LD50: 52 毫克/公斤
- 类别:有毒物品