L-Nmma Acetate N-单甲基-L-精氨酸单乙酸盐
CAS 53308-83-1 MFCD00069311
化学结构图
SMILES: CC(O)=O.CNC(=N)NCCC[C@H](N)C(O)=O
化学属性
| Mol. Formula | C9H20N4O4 |
|---|---|
| Mol. Weight | 248 |
别名和识别编码
| Chemical Name | L-Nmma Acetate |
|---|---|
| CAS Number | 53308-83-1 |
| Synonym | ANO 1020 L-NMMA Nω-Methyl-L-arginine acetate salt Nω-Methyl-L-arginine acetate salt L-NMMA N5-(Methylamidino)-L-ornithine acetate salt NG-Monomethyl-L-arginine acetate salt N5-(Methylamidino)-L-ornithine acetate salt N5-[Imino(methylamino)methyl]-L-ornithine Acetate NG-Methyl-L-arginine acetate salt NG-Monomethyl-L-arginine acetate salt Tilarginine Acetate |
| MDL Number | MFCD00069311 |
| PubChem Substance ID | 87573320 |
| Beilstein Registry Number | 6674255 |
| Reaxys-RN | 6674255 |
| Merck Number | 6022 |
| Chemical Name Translation | N-单甲基-L-精氨酸单乙酸盐 |
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分类
- Application Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling Enzymes, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, L to O, M, NOS Inhibitors, Nitric Oxide Metabolism, Nitric Oxide Synthase (iNOS), Nitric Oxide Synthase Regulators, Nitric Oxide and Cell Stress, Peptides and Proteins, Peptides for Cell Biology
- {SNA} Application Index, Bioactive Small Molecule Alphabetical Index, Cell Signaling Enzymes, Enzyme Inhibitor
- {SNA} Amino Acids, I - Z, Modified Amino Acids, 生化试剂
产品应用
- A potent inhibitor of NO synthase of adrenal glands, brain, and vascular endothelial cells.
相关文献及参考
- Rees, D.D., et al.: Br. J. Pharmacol., 101, 746 (1990),
- McCall, T.B., et al.: Br. J. Pharmacol., 102, 234 (1991),
- Sakuma, I., et al., Identification of arginine as a precursor of endothelium-derived relaxing factor. Proc. Natl. Acad. Sci. U. S. A. 85 , 8664-8667, (1988) 摘要
- von Bargen, K., et al., Nitric Oxide-Mediated Intracellular Growth Restriction Of Pathogenic Rhodococcus Equi Can Be Prevented By Iron. Infect. Immun. 79 , 2098-111, (2011) 摘要
- Butler, J.S., et al., Protein-arginine Methyltransferase 1 (PRMT1) Methylates Ash2L, A Shared Component Of Mammalian Histone H3K4 Methyltransferase Complexes. J. Thorac. Cardiovasc. Surg. 286 , 12234-44, (2011) 摘要
- Merck 14 ,6022
