CAS 521-11-9 MFCD00021158-Mestanolone 美雄诺龙 TAO{mole}

Mestanolone 美雄诺龙

CAS 521-11-9 MFCD00021158

化学结构图

SMILES: C[C@]12CCC(=O)C[C@@H]1CC[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1CC[C@]2(C)O

化学属性

Mol. Formula	C20H32O2
Mol. Weight	304.52
Appearance	结晶（乙酸乙酯）。熔点224-226℃。溶于丙酮、乙醇、乙醚乙酸乙酯，不溶于水。
Melting Point	191 °C

别名和识别编码

Chemical Name	Mestanolone
CAS Number	521-11-9
Synonym	17a-methyl-5a-androstan-17b-ol-3-one 5-alpha-Androstane-17-alpha-methyl-17-beta-ol-3-one Preroide 3-KETO-17B-HYDROXY-17A-METHYL-5A-ANDROSTANE 17alpha-Methyl-5alpha-dihydrotestosterone 17A-METHYLANDROSTAN-17B-OL-3-ONE mestanolone 17-alpha-Methyldihydrotestosterone 17ALPHA-甲基雄甾烷-17BETA-醇-3-酮 17α-甲基雄甾-17β-醇-酮 ######## 17ALPHA-METHYLDIHYDROTESTOSTERONE (5S,8R,10S,13S,17S)-17-Hydroxy-10,13,17-trimethyl-hexadecahydro-cyclopenta[ METHYLANDROSTANOLONE 17alpha-Methyl-17beta-hydr 17ALPHA-METHYLANDROSTAN-17BETA-OL-3-ONE 5ALPHA-ANDROSTANE-17ALPHA-METHYL-17BETA-OL-3-ONE 5α-雄甾烷-17α-甲基-17β-醇-3-酮 Methyldihydrotestosterone 17a-methyldihydrotestosterone Androstalone 17-HYDROXY-10,13,17-TRIMETHYLHEXADECAHYDROCYCLOPENTA[A]PHENANTHREN-3-ONE Mestalone Tantarone MESTALINE 17a-meth 美雄诺龙 17a-Methyldihydrotestosterone; 17a-Methyl-5a-androstan-17b-ol-3-one Methylantalon METHYLDIHYDROTESTOSTERONE 17α-甲基二氢睾酮 17β-羟基-17α-甲基-5α-雄甾烷-3-酮 5α-雄甾烷-17& 17b-羟基-17a-甲基-5a-雄甾烷-3-酮 Methybol (5S,8R,10S,13S,17S)-17-Hydroxy-10,13,17-trimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-one MESTANOLONE 5-ALPHA-ANDROSTAN-17-A 17α-甲基二氢睾酮 17β-羟基-17α-甲基雄甾(烷)-3-酮 17-beta-hydroxy-17-methyl-5 甲二氢睾酮雄甾烷醇酮 17-beta-hydroxy-17-methyl-5-alpha-androstan-3-on 17BETA-HYDROXY-17ALPHA-METHY 美睾酮加氢甲基睾酮 17β-羟基-17α-甲基-5α-雄甾烷-3-酮 M
MDL Number	MFCD00021158
PubChem Substance ID	10633
EC Number	208-302-6
Chemical Name Translation	美雄诺龙
Merck Number	5915
Wiswesser Line Notation	L E5 B666 OVTJ A1 E1 FQ F1
Beilstein Registry Number	3207223
InChI	InChI=1S/C20H32O2/c1-18-9-6-14(21)12-13(18)4-5-15-16(18)7-10-19(2)17(15)8-11-20(19,3)22/h13,15-17,22H,4-12H2,1-3H3/t13-,15+,16-,17-,18-,19-,20-/m0/s1

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产品应用

Anabolic steroid.

安全信息

RTECSBV8064500

GHS Symbol

Precautionary statements

P281 Use personal protective equipment as required. 使用所需的个人防护装备。

Signal word Warning

Hazard statements

H351 Suspected of causing cancer 怀疑致癌

Hazard Codes Xn

WGK Germany3

Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

Safety Statements

S22 Do not breathe dust 不要吸入粉尘；
S36 Wear suitable protective clothing 穿戴适当的防护服；

Risk Statements

R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1240 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,817,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,817,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,817,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,817,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 160 mg/kg
SEX/DURATION            : female 14-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - urogenital system
REFERENCE :
   ENDOAO Endocrinology (Baltimore).  (Williams & Wilkins Co., 428 E. Preston
   St., Baltimore, MD 21203) V.1-    1917-  Volume(issue)/page/year:
   94,979,1974

其他信息

MOL 文件:521-11-9.mol
Sigma Aldrich:521-11-9(sigmaaldrich)
方法一:用17α-甲基-3,17β-雄甾烷二醇经铬酸氧化制得。
用途一:用于男性性腺功能减退及精子减少性不育，去氢甲基睾丸素的中间体。
MSDS 信息:Mestanolone(521-11-9).msds
上游原料:铬酸 --> 5alpha-雄烷二醇
图谱信息:美雄诺龙(521-11-9)红外图谱(IR1) 美雄诺龙(521-11-9)红外图谱(IR2) 美雄诺龙(521-11-9)质谱(MS)