CAS 52-89-1 MFCD00064553-L-Cysteine Hydrochloride L-巯基丙氨酸盐酸盐 TAO{mole}

L-Cysteine Hydrochloride L-巯基丙氨酸盐酸盐

CAS 52-89-1 MFCD00064553

化学结构图

SMILES: Cl.NC(CS)C(=O)O

化学属性

Mol. Formula	C3H8ClNO2S
Mol. Weight	157.62
Density	1.422
TSCA	Yes
Melting Point	140-142°C
Solubility	可溶
Appearance	-16.5 (H2O), [α] D 其mp为175℃, 分解温度175℃，等电点5.07, [α] 25 L-半胱氨酸是含硫非必需氨基酸。在生物体内，由甲硫氨酸的硫原子置换丝氨酸的羟基氧原子并经膀硫醚而合成。 L-半胱氨酸可生成谷膀甘肽，参与细胞的还原过程和肝脏内的磷脂代谢，能保护肝细胞不受损害，并能刺激造血机能，增加白细胞、促进皮肤损害的修复。 +6.5 (5mol/L, HCl)。白色结晶或结晶性粉末，微臭，味酸，易溶于水、氨水、乙酸、微溶于乙醇、丙酮、乙酸乙酯、苯、二硫化碳、四氯化碳。对酸稳定，而在中性或微碱性溶液中易被空气氧化成胱氨酸，微量铁及重金属离子可促进氧化。其盐酸盐较稳定，故一般都制成盐酸盐。

别名和识别编码

Chemical Name	L-Cysteine Hydrochloride
CAS Number	52-89-1
Alfabeta Name	CYSTEINEHYDROCHLORIDEANHYDROUS L-
MDL Number	MFCD00064553
Synonym	L-Cysteine (hydrochloride) {LY} L-Cysteine (hydrochloride) {} {LY} L-Cysteine (hydrochloride) {} {} {LY} L-Cysteine (hydrochloride) {} {} {} {LY} L-Cysteine (hydrochloride) {} {} {} {} {LY} L-Cysteine (hydrochloride) {} {} {} {} {} {LY} L-Cysteine (hydrochloride) {} {} {} {} {} {} {LY} L-Cysteine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Cysteine (hydrochloride) {} {} {} {} {} {} {} {} {LY} L-Cysteine (hydrochloride) {} {} {} {} {} {} {} {} {} {LY} L-Cysteine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Cysteine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {LY} L-Cysteine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Cysteine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Cysteine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Cysteine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Cystein
EC Number	200-157-7
Beilstein Registry Number	3560277
Merck Number	14,2781
PubChem Substance ID	60960
Chemical Name Translation	L-巯基丙氨酸盐酸盐
Wiswesser Line Notation	SH1YZVQ &GH -L
LabNetwork Molecule ID	LN00173748
InChI	InChI=1S/C3H7NO2S.ClH/c4-2(1-7)3(5)6;/h2,7H,1,4H2,(H,5,6);1H/t2-;/m0./s1
Canonical SMILES	N[C@@H](CS)C(O)=O.[H]Cl

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

NMDA 谷氨酸能受体激动剂，在高浓度时，也是AMPA谷氨酸能受体激动剂。

安全信息

Warnings IRRITANT

Signal word Warning

GHS Symbol

WGK Germany3

Safety Statements

S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S36 Wear suitable protective clothing 穿戴适当的防护服；

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

Precautionary statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P305+P351+P338

RTECSHA2275000

Storage condition 2-8°C, sealed storage, away from moisture {LY} 2-8°C, sealed storage, away from moisture Hygroscopic Store at RT. {} {LY} 2-8°C, sealed storage, away from moisture {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {} {LY}

Hazard statements

H315 Causes skin irritation 会刺激皮肤
H319 Causes serious eye irritation 严重刺激眼睛
H335 May cause respiratory irritation 可能导致呼吸道刺激

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes Xi

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD691-490

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 771 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JJANAX Japanese Journal of Antibiotics.  (Japan Antibiotics Research Assoc.,
   2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan)  V.21-    1968-
   Volume(issue)/page/year: 38,137,1985

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BJCAAI British Journal of Cancer.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1947-  Volume(issue)/page/year:
   6,160,1952

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Fibroblast
DOSE/DURATION           : 2 gm/L
REFERENCE :
   FCTOD7 Food and Chemical Toxicology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.20-    1982- Volume(issue)/page/year:
   22,623,1984

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 20 mg/plate
REFERENCE :
   FCTOD7 Food and Chemical Toxicology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.20-    1982- Volume(issue)/page/year:
   22,623,1984

其他信息

图谱信息:L-半胱氨酸盐酸盐(无水物)(52-89-1)核磁图( 13 CNMR) L-半胱氨酸盐酸盐(无水物)(52-89-1)红外图谱(IR2) L-半胱
强酸味，无臭，仅有痕量亚硫酸盐气味。它在动植物体内是各组织细胞用来防御有害物质和增加活力的一种氨基酸，也是组成蛋白质的20多种氨基酸之一，并且是唯一具有活性巯基(-SH)的氨基酸。
所属类别二:生物化学品: 生化试剂: 氨基酸及其衍生物
上游原料:乙醇 --> 氯化亚锡 --> L-胱氨酸 --> L-半胱氨酸 --> 噻唑啉
用途四:用于生化研究，用作测
下游产品:N-叔丁氧羰基-S-三苯甲基-L-半胱氨酸 --> 羧甲司坦
图谱信息:L-半胱氨酸盐酸盐(无水物)(52-89-1)核磁图( 13 CNMR) L-半胱氨酸盐酸盐(无水物)(52-89-1)红外图谱(IR2) L-半胱氨酸盐酸盐(无水物)(52-89-1)红外图谱(IR1) L-半胱氨酸
用
方法二:方法一、水解-电解法以猪毛、头发为原料经水解、调胱氨酸等电点分离出胱氨酸，再电解还原胱氨酸，制得半胱氨酸。水解分离出胱氨酸猪毛、头发[HCl, 117℃, 7h]→[酸水解]水解液[NaOH, pH4.8]→[中和]L-胱氨酸（粗品）电解还原在两个分开的池子中，一个池子内灌入1mol/L 的HCl插入墨棒，接电源正极，此池为阳极，另一池内灌入胱氨酸的盐酸溶液（胱氨酸：浓HCl:水=1：1：4），插入铅板，接电源负极，此池为阴极。在两池之间加盐桥连接。接通电源调节电流5A，进行电解，约6-7h 电解完成。取电解液少许滴加吡啶，无浑浊表明电解完成。 L-胱氨酸[HCl]→[电解还原]L-半胱氨酸盐酸盐 [脱色、浓缩、结晶]→L-半胱氨酸盐酸盐结晶脱色、浓缩、结晶电解完成后，切断电源，按投料量加入10g/L(1%)活性炭，加热至70℃, 保温半小时。过滤取滤液。并将其减压浓缩至有结晶为止，搅拌使结晶完全析出，过滤取结晶，用95%乙醇洗涤，于60℃以下真空干燥，即得无结晶水的L-半胱氨酸盐酸盐。方法二、酶法 DL-2-氨基二氢噻唑啉-4-羧酸(DL-ATC)酶水解法
用途三:用于治疗放射性药物中毒、重金属中毒、中毒性肝炎、血清病等
MSDS 信息:L-Cysteine hydrochloride anhydrous(52-89-1).msds
参考质量标准:含量不少于99.0%；比旋光度[α] 25 D +5.7°-+6.8°；水分8.0%- 12.0%，灼烧残渣(以SO 2- 4 计)小于0.4%，氯化物(
用途六:NMDA 谷氨酸能受体激动剂，在高浓度时，也是AM
L-半胱氨酸盐酸盐(无水物)价格(试剂级):更新日期产品编号产品名称包装价格 2010/05/25 L06328 L-无水巯基丙氨酸盐酸盐, 98% L-Cysteine hydrochloride, anhydrous, 98% 25g 426元 2010/05/25 L06328 L-无水巯基丙氨酸盐酸盐, 98% L-Cysteine hydrochloride, anhydrous, 98% 100g 1442元
用途五:制药、食品。
食品添加剂最大允许使用量最大允许残留量标准:添加剂中文名称允许使用该种添加剂的食品中文名称添加剂功能最大允许使用量（g/kg）最大允许残留量（g/kg） L-半胱氨酸盐酸盐发酵面制品面粉处理剂 0.06
敏感性:Hygroscopic
参考质量标准:含量不少于99.0%；比旋光度[α] 25 D +5.7°-+6.8°；水分8.0%- 12.0%，灼烧残渣(以SO 2- 4 计)小于0.4%，氯化物(以Cl计)含量19.8%-20.8%，硫酸盐(以SO 2- 4 计)含量小于0.03%，As含量小于0.00015%，铁含量(Fe)小于0.003%，重金属含量(以Pb计)小于0.0015%，水溶解性试验、纸层析合格。
用途一:用于医药、食品等