Tris(2-carboxyethyl)phosphine hydrochloride 三(2-甲酰乙基)膦盐酸盐
CAS 51805-45-9 MFCD00145469
化学结构图
SMILES: Cl.O=C(O)CCP(CCC(=O)O)CCC(=O)O
化学属性
| Mol. Formula | C9H15O6P·HCl |
|---|---|
| Mol. Weight | 286.64 |
| Melting Point | 177°C |
| Solubility | Soluble in water (5 mg/ml), and methanol., Soluble in water (5 mg/ml), and methanol. |
| TSCA | No |
| Density | 1.041 g/mL at 25 °C |
| Refractive index | n20/D 1.367 |
| Appearance | powder |
| Stability | 对湿度敏感 |
别名和识别编码
| Chemical Name | Tris(2-carboxyethyl)phosphine hydrochloride |
|---|---|
| CAS Number | 51805-45-9 |
| Synonym | TCEP*HCL TRIS(CARBOXYETHYL)PHOSPHINE & TRIS-(2-CARBOXYETHYL)PHOSPHINE HYDROCHLORIDE (TCEP HCL) TRIS(CARBOXYETHYL)PHOSPHINE HYDROCHLORIDE TRIS(2-CARBOXYETHYL)PHOSPHINE HYDROCHLORIDE Tris(2-carboxyethyl)phosphonium Hydrochloride 3,3',3''-Phosphinidynetrispropanoic Acid Hydrochloride Tris(2-carboxyethyl)phosphine,hydrochloride,99% TCEP HCL 3,3',3''-PHOSPHINIDYNE-TRIPROPIONIC ACID HYDROCHLORIDE 三(2-羰基乙基)磷盐酸盐 TCEP HCl TRIS(2-CARBOXYETHYL)PHOSPHINE, HCL 0.5M TCEP TCEP TRIS(2-CARBOXYETHYL)PHOSPHINE HYDROCHLORIDE 99% Tris(2-carboxyethyl)phosphine-D16DCl TRIS-(2-CARBOXYETHYL)PHOSPHINE HYDROCHLORIDE (TCEP) Tris(2-carboxyethyl)phosphine Hydrochloride 三(2-羧乙基)膦 盐酸盐 溶液 Tris(carboxyethyl)phosphine Hydrochloride 三(2-羰基乙基)磷盐酸盐;TCEP; 3,3',3''-PHOSPHINETRIYL-TRIPROPIONIC ACID HYDROCHLORIDE TRI(2-CARBOXYETHYL)PHOSPHINE HYDROCHLORIDE Tris-(2-carboxyethy)phosphine hydrochloride 三(2-羧乙基)磷盐酸盐 三(2-羧乙基)膦 盐酸盐 三(2-甲酰乙基)膦盐酸盐 TCEP, HYDROCHLORIDE |
| MDL Number | MFCD00145469 |
| PubChem Substance ID | 87577397 |
| Beilstein Registry Number | 3724376 |
| Merck Number | 9085 |
| EC Number | 250-023-7 |
| Chemical Name Translation | 三(2-甲酰乙基)膦盐酸盐 |
| Reaxys-RN | 3724376 |
| LabNetwork Molecule ID | LN00193416 |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Antioxidants and Reducing Agents for Protei
- {SNA} Antioxidants and Re
- {SNA} Acrylamides, SDS-PAGE, 分子生物学, 蛋白电泳,
- {SNA} Acrylamides, Molecular Biology, Protein Electrophoresis, Proteomics, SDS-PAGE
- {SNA} Cell Lysis and Protein Extraction Reagents, Chemical Modification Reagents, Chemical Synthesis, Native Protein Sample Preparation, Others, Proteomics, Reduction, Synthetic Reagents
- {SNA} Cell Lysis and Protein Extraction Reagents, Chemical Modification Reagents, Chemical Synthesis, Molecular Biology, Native Protein Sample Preparation, Others, Proteomics, Reduction, Synthetic Reagents
- {SNA} Acryla
产品应用
- 水溶性试剂，用于二硫化物的选择性还原。在质谱应用中比 DTT 更稳定。
- 用于在水中进行的二硫化物选择性还原。
- 碱化后，该水溶性配体可通过水性洗涤反应粗产物实现钌系复分解催化剂的简单去除。
相关文献及参考
- Neuburger, M., et al.: Eur. J. Biochem., 267, 2882 (2000),
- Krijt, J., et al.: Clin. Chem., 47, 1821 (2001),
- Yen, T.-Y., et al.: J. Mass Spectrom., 37, 15 (2002),
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P302+P352+P332+P313+P362+P364
- P303+P361+P353
- P304+P340+P310
- P304+P340+P312
- P305+P351+P338
- P305+P351+P338+P337+P313
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P332+P313
- P337+P313
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S27 Take off immediately all contaminated clothing 立即脱掉全部污染的衣服；
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
- S37 Wear suitable gloves 戴适当手套；
- S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
- R34 Causes burns 会导致灼伤
- R36 Irritating to eyes 刺激眼睛
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
其他信息
- Alfa Aesar:三(2-甲酰乙基)膦盐酸盐,98% Tris(2-carboxyethyl)phosphine hydrochloride, 98%(51805-45-9)
- TCEP Hydrochloride is a water soluble, non-thiol, strong reducing agent shown to cleave disulfide bonds. Reports indicate that TCEP Hydrochloride can rapidly reduce stable alkyl disulfides, including DTT. TCEP Hydrochloride has been observed to reduce DHA in a solution of EDTA and metaphosphoric acid, and used to conduct proteolysis and Hydrogen/Deuterium exchange. Binding studies demonstrate that TCEP Hydrochloride does not bind Hg2+, and its binding efficacy to NF-κB-DNA has been tested in vitro.
- Acros Organics:三(2-羧乙基)磷盐酸盐 Tris(2-carboxyethyl)phosphine hydrochloride, 98%(51805-45-9)
- color:white
- F:10
- Sigma Aldrich:51805-45-9(sigmaaldrich)
