Canthaxanthin 斑蝥黄
CAS 514-78-3 MFCD00016364
化学结构图
SMILES: CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)C(=O)CCC2(C)C)C(C)(C)CCC1=O
化学属性
| Mol. Formula | C40H52O2 |
|---|---|
| Mol. Weight | 564.92 |
| Appearance | 一种类胡萝卜素色素。深紫色晶体或结晶性粉末。熔点约210℃(分解)。对氧及光不稳定。需贮存于充惰性气体的遮光性容器内。溶于氯仿(10%)。微溶于植物油(0.005%)、丙酮(0.03%)。不溶于水、乙醇、丙二醇。稳定的工业产品为溶于油脂或有机溶剂中的溶液形式，或水分散性的橙至红色粉末或颗粒形式。着色后色调不受pH值影响，对日光亦相当稳定，不易褪色。 天然品存在于某种蘑菇、甲壳类、鱼类、藻类、蛋、血液、肝脏等中。 |
别名和识别编码
| Chemical Name | Canthaxanthin |
|---|---|
| CAS Number | 514-78-3 |
| Synonym | β-胡萝卜素-4,4′-二酮 E 161g 2,4,4-Trimethyl-3-[3,7,12,16-tetramethyl-18-(2,6,6-trimethyl-3-oxo-1-cyclohexenyl)octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohex-2-en-1-one 4',4-DIOXO-B-CAROTENE 4,4'-Diketo-β-carotene 4,4'-Dioxo-β-carotene 4,4'-DIKETO-BETA-CAROTENE 4,4'-Diketo-?-carotene 4,4'-Dioxo-?-carotene 4’-dione,all-trans-.beta.-Carotene-4 B,B-CAROTENE-4,4'DIONE BETA,BETA'-CAROTIN-4,4'-DIONE BETA,BETA-CAROTENE-4,4'-DIONE C.I. 40850 C.I. Food Orange 8 Cantaxanthin Canthaxanthin Canthaxanthin (trans) Canthaxanthine Carophyll Red Carophyll red E 161 G E 161g FOOD ORANGE 8 Food Orange 8 Food Orange 8 (C.I.) L-Orange 7 { |
| Beilstein Registry Number | 1898520 |
| MDL Number | MFCD00016364 |
| EC Number | 208-187-2 |
| Chemical Name Translation | 斑蝥黄 |
| Merck Number | 13,1758 |
| LabNetwork Molecule ID | LN01806096 |
| PubChem Substance ID | 5281227 |
| InChI | InChI=1S/C40H52O2/c1-29(17-13-19-31(3)21-23-35-33(5)37(41)25-27-39(35,7)8)15-11-12-16-30(2)18-14-20-32(4)22-24-36-34(6)38(42)26-28-40(36,9)10/h11-24H,25-28H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,29-15+,30-16+,31-19+,32-20+ |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- Alphabetic, Analytical Standards, Analytical/Chromatography, C, CA - CG, Carotenoid, Chromatography, E numbers (Food Additives), E100–E199 (colors), E161g, Fat-Soluble Vitamins, Food & Beverage Standards, Food Dyes, Food Residue Analysis, Life Sciences Standards, Market Segments, Natural Compounds, Neats and Solutions, Nutrition Research, Phytochemicals by Chemical Classification, Standards for Pharma Clinical Forensic & Veterinary Analysis, Vitamin A, Vitamins
- {SNA} Additional Standards, All alphabetical sorted,
- {SNA} Additional Standards,
- {SNA} Additional Standards,
产品应用
- Oral suntanning agent
相关文献及参考
- [2]. Huang DS, et al. Inhibitory effects of canthaxanthin on in vitro growth of murine tumor cells. Cancer Lett. 1992 Aug 31;65(3):209-13.
- [3]. Palozza P, et al. Canthaxanthin supplementation alters antioxidant enzymes and iron concentration in liver of Balb/c mice. J Nutr. 2000 May;130(5):1303-8.
- [4]. Chew BP, et al. A comparison of the anticancer activities of dietary beta-carotene, canthaxanthin and astaxanthin in mice in vivo. Anticancer Res. 1999 May-Jun;19(3A):1849-53.
- [5]. Grubbs CJ, et al. Effect of canthaxanthin on chemically induced mammary carcinogenesis. Oncology. 1991;48(3):239-45.
- Beil. 7 ,IV,2680
- Butler, M., et al.: Arch. Biochem. Biophys., 504, 154 (2010),
- Merck 14 ,1753
- Short: EINECS Title: EINECS (European Inventory of Existing Commercial Chemical Substances) Source: Official Journal of the European Communities Volume: C 146 A (15.06.1990) Page: 1 Year: 1990 Internet Resource: http://ecb.jrc.e
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 10 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : SCPHA4 Scientia Pharmaceutica. (Oesterreichische Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria) V.1- 1930- Volume(issue)/page/year: 47,39,1979
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - man DOSE/DURATION : 86 mg/kg/15W-I TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - retinal changes (pigmentary depositions, retinitis, other) REFERENCE : MJAUAJ Medical Journal of Australia. (Australasian Medical Pub. Co. Ltd., 71-79 Arundel St., Glebe, N.S.W., Australia) V.1- 1914- Volume(issue)/page/year: 143,622,1985
其他信息
- 上游原料:beta-胡萝卜素
- MOL 文件:514-78-3.mol
- 用途一:食用橙色色素，用作饮料、冰激凌、华夫等无辅料饼干k调味酱、番茄加工品、肉类加工品等。适量添加于白色蛋糕预制粉，可带杏子色调，烘烤后色素残留率可达96%。猪肉制的香肠中添加11mg/kg可得与牛肉制品相同的色调。
- 鉴别试验:溶解性不溶于水；不溶于乙醇；几不溶于植物油；溶于氯仿。按OT-42方法测定。 在环己烷溶液中，于468nm和472nm波长处有最大吸收峰。 类胡萝卜素阳性试验在丙酮溶液中的颜色，在相继添加5%亚硝酸钠溶液和1mol/L硫酸后消失。
- 使用限量:FAO/WHO(1984，mg/kg)：食用油脂按GMP；小虾、龙虾罐头及速冻品，肉汤、羹，30；果酱和果冻200；冷饮100。 FDA，§73.75(2000)：30mg/456g各类食品。 日本规定：在橙汁饮料中的添加量为1～5g/1000L；冰激凌中为10～30mg/kg；番茄汤料≥6mg/kg；番茄酱1mg/1.5g番茄固形物。
- 毒性:ADl 0～0.03(FAOWHO，2001)。 LD 50 ≥10g/kg(小鼠，经口)。
- 方法一:由β-胡萝卜素氧化而得。
- Sigma Aldrich:514-78-3(sigmaaldrich)
- 参考质量标准:FAO/WHO，1998 总色素含量(以斑蝥黄计) ≥96% 硫酸盐灰分(GT-5，试样2g) ≤0.1% 副色素 ≤5% 铅(GT-18-3) ≤2mg/kg
- 含量分析:精确称取试样约0.1g，然后按OT-15中方法一测定。 吸光系数E 1cm 1% =2200；最大吸收峰的波长约为470nm。W=9.1g；V 1 =V 2 =V 3 =100ml；v 4 = v 4 =5ml
