(S)-(+)-Ibuprofen (S)-(+)-布洛芬
CAS 51146-56-6 MFCD00069289
化学结构图
SMILES: CC(C)CC1=CC=C(C=C1)[C@H](C)C(O)=O
化学属性
| Mol. Formula | C13H18O2 |
|---|---|
| Mol. Weight | 206 |
| Melting Point | 49-53 |
| Density | 1.422 |
| Boiling Point | 113 |
别名和识别编码
| Chemical Name | (S)-(+)-Ibuprofen |
|---|---|
| CAS Number | 51146-56-6 |
| Alfabeta Name | ISOBUTYLPHENYLPROPANOICACID S24(())--- |
| MDL Number | MFCD00069289 |
| Synonym | (S)-(+)-布洛芬 (S)-(+)-2-(4-异丁基苯基)丙酸 (S)-(+)-4-异丁基-α-甲基苯乙酸 (S)-(+)-2-(4-异丁基苯基)丙酸 (S)-(+)-4-异丁基-α-甲基苯乙酸 (?S)- (S)-(+)-2-(4-异丁基苯基)丙酸 (S)-(+)-4-异丁基-α-甲基苯乙酸 (S)-(+)-2-(4-异丁基苯基)丙酸 (S)-(+)-4-异丁基-α-甲基苯乙酸 S-(+)-IBU S-(+)-IBU |
| Beilstein Registry Number | 3590022 |
| PubChem Substance ID | 87571895 |
| Reaxys-RN | 3590020 |
| EC Number | 250-023-7 |
| Chemical Name Translation | (S)-(+)-布洛芬 |
| LabNetwork Molecule ID | LN00177146 |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- Inhibitors
- {SNA} Asymmetric Synthesis, Carboxylic Acids, Chemical Synthesis, Chiral Building Blocks, Organic Building Blocks
- {SNA} Asymmetric Synthesis, Bioactive Small Molecules, Carboxylic Acids, Cell Biology, Chemical Synthesis, Chiral Building Blocks, I, Organic Building Blocks
- Chiral Reagents
- Phar
产品应用
- A nonsteroidal anti-inflammatory drug (NSAID); activity resides primarily in the (S)-isomer.
相关文献及参考
- Busson, M., et al.: J. Int. Med Res., 14, 53 (1986),
- Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993),
- Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),
- Mehvar, et al., Liquid chromatography assay of ibuprofen enantiomers in plasma. Clin. Chem. 34 , 493-496, (1988) 摘要
- Mehvar, et al., Pharmacokinetic analysis of the enantiomeric inversion of chiral nonsteroidal antiinflammatory drugs. Pharmacol. Res. 5 , 76-79, (1988) 摘要
- Jeffrey, et al., The site of inversion of R(−)-ibuprofen: Studies using rat in situ isolated perfused intestine/liver preparations. J. Pharm. Pharmacol. 43 , 715-720, (1991) 摘要
安全信息
- H315 Causes skin irritation 会刺激皮肤
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P281 Use personal protective equipment as required. 使用所需的个人防护装备。
- P301+P312
- P302+P350
- P305+P351+P338+P337+P313
- P332+P313
- P337+P313
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
GHS Symbol
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- R22 Harmful if swallowed 吞咽有害
- R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
