9H-Dibenzo(b,d)pyran-9-one,3-(1,1-dimethylheptyl)-6,6a,7,8,10,10a-hexahydro-1-hydroxy- 6,6-dimethyl-, trans-(+-)-
CAS 51022-71-0 MFCD00941490
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信息真实价格透明
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专业采购外包团队在线服务
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分类
- Analytical Standards, Analytical/Chromatography, Bioactive Small Molecules, Cannabinoids, Cannabiol, Cell Biology, Cell Signaling and Neuroscience, Chemical Structure, Chromatography, Drugs & Metabolites, Drugs of Abuse, Forensic and Veterinary Standards, N, Neat Compounds, Neurobiology, Neuroscience, Pharmacologicals
- {SNA} Analytical Standards, Analytical/Chromatography, Bioactive Small Molecules, Cannabinoids, Cannabiol, Cell Biology, Cell Signaling and Neuroscience, Chemical Structure,
产品应用
- A synthetic cannabinoid with antiemetic, antiglaucoma, and CNS activity. Antiemetic.
相关文献及参考
- Rubin, A., et al.: Clin. Pharmacol. Ther., 22, 85 (1977),
- Stark, P., et al.: J. Pharmacol. Exp. Ther., 214, 124 (1980),
- Souter, R.W., et al.: Anal. Profiles Drug Subs., 10, 499 (1981),
- Merck 14 ,6342
安全信息
GHS Symbol
- H302 Harmful if swallowed 吞食有害
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- R22 Harmful if swallowed 吞咽有害
T
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - cat DOSE/DURATION : >1 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - ataxia REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 9,185,1987
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : >5 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - somnolence (general depressed activity) Behavioral - ataxia REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 9,185,1987
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >1000 mg/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - ataxia Gastrointestinal - hypermotility, diarrhea REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 9,185,1987
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1000 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - Straub tail REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 9,185,1987
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TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 348 mg/kg SEX/DURATION : female 14-22 day(s) after conception lactating female 20 day(s) post-birth TOXIC EFFECTS : Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4) REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 48,A120,1979