CAS 492-80-8 MFCD00036224-Auramine Auramine TAO{mole}

Auramine Auramine

CAS 492-80-8 MFCD00036224

化学结构图

SMILES:

化学属性

Mol. Formula	C17H21N3
Mol. Weight	267.41
Melting Point	138 ºC
Density	1.01

别名和识别编码

Chemical Name	analytical standard
Synonym	C.I. Basic Yellow 2, Free Base TETRAMETHYL44DIAMINODIPHENYLMETHYLENEIMINE 奥拉明O 4,4'-碳亚氨基二[N,N-二甲基]苯胺 Apyonin Auramin 4,4'-carbonimidoylbis[N,N-dimethylaniline] C.I. Solvent Yellow 34 4,4'-dimethylaminobenzophenonimide 4,4'-(Imidocarbonyl)bis(N,N-dimethylaniline); 4,4'-Dimethylaminobenzophenonimide; Auramine N Base; Auramine O Base; Auramine OAF; Auramine SS; Auramine base; Baso Yellow 124; Brilliant Oil Yellow; C.I. 41000B; Orient Oil Yellow 101; Solvent Yellow 34; Waxoline Brilliant Oil Yellow 4,4'-(imidocarbonyl)bis(n,n-dimethyl-anilin C.I. Basic Yell 4,4'-Dimethylaminobenzophenonimide 4,4'-Carbonimidoyl 4,4'-carbonimidoylbis(n,n-dimethylbenzenamine) Auramine OAF 4,4'-Dimethylaminobenzophenonimide 4,4'-(Imidocarbonyl)bis(N,N-Dimethylaniline) C.I.碱性黄2 Auramine SS 4,4'-二甲基氨基二苯甲酮亚胺溶剂黄 34 Carbonoimidoylbis(N,N-dimethylbenzenamine) {uni C.I.41000:1 4,4'-(Imidocarbonyl)bis(N,N-dimethylaniline) C.I. 41000B {Chemical Benzenamine, 4,4’-carbonimidoylbis [N,N-dimethyl- 碱性嫩黄 4,4'-Carbonimidoylbis[N,N-dimethylanilin] Bis(p-dimethylaminophenyl)methyleneimine Auremine {h {haz Auramine Waxoline yellow D Auramine base 4,4'-carbonimidoylbis[N,N-dimethylaniline] Tetramethyldiaminodiphenylacetimine 4,4'-carbonimidoylbis[N,N-dimethyl-Benzenamine 4, 4 -Carbonimdoylbis[N,N-dimethylaniline] Benzenamine, 4,4'-carbonimidoylbis[N,N-dimethyl- Blauramine Auramine Base
CAS Number	492-80-8
Beilstein Registry Number	2215338
MDL Number	MFCD00036224
EC Number	207-762-5
Chemical Name Translation	Auramine
Wiswesser Line Notation	1N1&R DYUM&R DN1&1

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分类

{SNA} Alphabetical Index of Analytical Standards, Chemical Class, A, AR to AZ, All Alphabetically Sorted, All alphabetical sorted, Analytical Standards, Analytical/Chromatography, Aromatics, Chromatography, Colors, Food & Beverage Standards, Food Color Additives, Life Sciences Standards, Other banned artificial food dyes
{uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; 1fragment
{SNA} A, AR to AZ, All Alphabetically Sorted, All alphabetical sorted, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Aromatics, Chemical Class,
{SNA} A,
{SNA

安全信息

Hazard statements

H351 Suspected of causing cancer 怀疑致癌
H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
H302 Harmful if swallowed 吞食有害
H319 Causes serious eye irritation 严重刺激眼睛

GHS Symbol

Precautionary statements

P305+P351+P338
P273 Avoid release to the environment. 避免释放到环境中。
P281 Use personal protective equipment as required. 使用所需的个人防护装备。

WGK Germany3

Signal word Warning

RTECSBY3500000

Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

Safety Statements

S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；

Hazard Codes Xn,N

Risk Statements

R51/53
R36 Irritating to eyes 刺激眼睛
R22 Harmful if swallowed 吞咽有害
R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 42 gm/kg/50W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
REFERENCE :
   AICCA6 Acta Unio Internationalis Contra Cancrum.  (Louvain, Belgium) V.1-20,
   1936-64.  For publisher information, see IJCNAW. Volume(issue)/page/year:
   19,483,1963

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 263 mg/kg/21W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   AICCA6 Acta Unio Internationalis Contra Cancrum.  (Louvain, Belgium) V.1-20,
   1936-64.  For publisher information, see IJCNAW. Volume(issue)/page/year:
   19,483,1963

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 29 gm/kg/52W
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Liver - tumors
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   BJCAAI British Journal of Cancer.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1947-  Volume(issue)/page/year:
   10,653,1956

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 37 gm/kg/87W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumor types after systemic administration not seen
   spontaneously
REFERENCE :
   AICCA6 Acta Unio Internationalis Contra Cancrum.  (Louvain, Belgium) V.1-20,
   1936-64.  For publisher information, see IJCNAW

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle weakness
REFERENCE :
   TLSMA6 Trudy Leningradskogo Sanitarno-Gigienicheskogo Meditsinskogo
   Instituta.  (Leningrad, Russia) V.1-145, 1949-82.  Discontinued.
   Volume(issue)/page/year: 105,45,1974

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 103 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PMRSDJ Progress in Mutation Research.  (Elsevier Science Pub. Co., Inc., 52
   Vanderbilt Ave., New York, NY 10017)  V.1-    1981- Volume(issue)/page/year:
   1,682,1981

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 250 ug/plate
REFERENCE :
   PMRSDJ Progress in Mutation Research.  (Elsevier Science Pub. Co., Inc., 52
   Vanderbilt Ave., New York, NY 10017)  V.1-    1981- Volume(

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 2 mg/disc
REFERENCE :
   PMRSDJ Progress in Mutat

TYPE OF TEST            : DNA inhibition
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 46,305,1977

TYPE OF TEST            : Gene conversion and mitotic recombination
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 78 ppm
REFERENCE :
   PMRSDJ Progress in Mutation Research.  (Elsevier Science Pub. Co., Inc., 52
   Vanderbilt Ave., New York, NY 10017)  V.1-    1981- Volume(issue)/page/year:
   1,481,1981

TYPE OF TEST            : Phage inhibition capacity
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 300 mg/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   41,532,1981

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Human Fibroblast
DOSE/DURATION           : 20 mg/L
REFERENCE :
   TXCYAC Toxicology.  (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
   Limerick, Ireland) V.1-    1973-  Volume(issue)/page/year: 21,151,1981

TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - hamster Embryo
DOSE/DURATION

其他信息

用途一:主要用于醋纤、棉织品的染色，还用于纸张、皮革、油漆等的着色
MOL 文件:492-80-8.mol
Sigma Aldrich:492-80-8(sigmaaldrich)