5-Methoxypsoralen 佛手苷内酯
CAS 484-20-8 MFCD00010272
信息真实价格透明
资金保障
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信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- A - D, Alphabetical, Analytical Standards, Analytical/Chromatography, Angelica, Carum, Chromatography, Citrus, Foeniculum, Life Sciences Standards, Natural Compounds, Phenylpropanes, Phytopharma Standards, Pimpinella, Standards by Plant Genus, Substance Classification
- {SNA} A - D,
- {S
- {uni_hamburg} no charge; oxygen heterocycle; carbocycle; aromatic; large ring; fused rings; 5ring; 6ring; 9ring; 10ring; 13ring; ester; lactone; ether; 1fragment
- {SNA} A - D, A-F, Alphabetical, Analytical Standards, Analytical/Chromatography, Angelica, Carum, Chromatography,
- {SNA} Citrus aurantium (Seville orange),
产品应用
- Naturally occurring analog of Psoralen ( P839800) and metabolite of 8-Methoxy Psoralen (M260795). Antipsoriatic.
相关文献及参考
- [2]. Li XJ, et al. Bergapten exerts inhibitory effects on diabetes-related osteoporosis via the regulation of the PI3K/AKT, JNK/MAPK and NF-κB signaling pathways in osteoprotegerin knockout mice. Int J Mol Med. 2016 Dec;38(6):1661-1672.
- Honigsmann, H., et al.: Br. J. Dermatol., 101, 369 (1979),
- Merck: 14,1157
- Merck: 14,1157 Beilstein:19(5)6,4
- Short: III/35C3
- Short: III/35D4
- [1]. Lee YM, et al. Effects of 5-methoxypsoralen (5-MOP) on arylamine N-acetyltransferase activity in the stomach and colon of rats and human stomach and colon tumor cell lines. In Vivo. 2005 Nov-Dec;19(6):1061-9.
- [1]. Lee YM, et al. Effects of 5-methoxypsoralen (5-MOP) on arylamine N-acetyltransferase activity in the stomach and colon of rats and human stomach and colon tumor cell lines. In Vivo. 2005 Nov-Dec;19(6):1061-9.
- [2]. Li XJ, et al. Bergapten exerts inhibitory effects on diabetes-related osteoporosis via the regulation of t
安全信息
GHS Symbol
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P302+P350
- P302+P352+P333+P313+P362+P364
- P308+P313
- P333+P313
- P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- H317 May cause an allergic skin reaction 可能导致皮肤过敏
- H350 May cause cancer 可能致癌
- H340 May cause genetic defects 可能导致遗传性缺陷
- H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
- R45 May cause cancer 可能致癌
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 8100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 48PRAW "Psoralens in Cosmetics and Dermatology, Proceedings of the International Symposium, Paris, 1981," Cahn, J., et al., eds., Paris, Pergamon Press France, 1981 Volume(issue)/page/year: -,303,1981
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >30 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 48PRAW "Psoralens in Cosmetics and Dermatology, Proceedings of the International Symposium, Paris, 1981," Cahn, J., et al., eds., Paris, Pergamon Press France, 1981 Volume(issue)/page/year: -,303,1981
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 9 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 48PRAW "Psoralens in Cosmetics and Dermatology, Proceedings of the International Symposium, Paris, 1981," Cahn, J., et al., eds., Paris, Pergamon Press France, 1981 Volume(issue)/page/year: -,303,1981
TYPE OF TEST : Cytogenetic analysis ROUTE OF EXPOSURE : Intraperitoneal TEST SYSTEM : Rodent - mouse DOSE/DURATION : 900 mg/kg REFERENCE : EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 25,302,1995
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 5600 mg/kg SEX/DURATION : female 6-15 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) REFERENCE : 48PRAW "Psoralens in Cosmetics and Dermatology, Proceedings of the International Symposium, Paris, 1981," Cahn, J., et al., eds., Paris, Pergamon Press France, 1981 Volume(issue)/page/year: -,303,1981
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 6720 mg/kg SEX/DURATION : female 7-18 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) REFERENCE : 48PRAW "Psoralens in Cosmetics and Dermatology, Proceedings of the International Symposium, Paris, 1981," Cahn, J., et al., eds., Paris, Pergamon Press France, 1981 Volume(issue)/page/year: -,303,1981
其他信息
- 图谱信息:佛手苷内酯(484-20-8)核磁图( 1 HNMR)
- 佛手苷内酯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 B2840 佛手苷内酯 Bergapten 5G 6030元 2014/06/02 B2840 佛手苷内酯 Bergapten 1G 1640元
- Sigma Aldrich:484-20-8(sigmaaldrich)
- MOL 文件:484-20-8.mol
- TCI Shanghai:佛手苷内酯 Bergapten,>;98.0%(GC)(484-20-8)
- F:8-10
- MSDS 信息:5-Methoxypsoralen(484-20-8).msds
- 上游原料:氢氧化钠 --> 盐酸 --> 乙酸乙酯 --> 甲醇 --> 硫酸 --> 二氯甲烷 --> N,N-二甲基甲酰胺 --> 碳酸钾 --> 三氯甲烷 --> 硫酸钠 --> 三乙胺 --> 氨 --> 碳酸氢钠 --> 1,4-二氧六环 --> 甲酸 --> 叔丁醇 --> 氯化锌 --> 碘化钾 --> 碘 --> 四丁基溴化铵 --> 三氟化硼乙醚 --> 醋酸钯 --> 2,6-二甲基吡啶 --> 3-溴丙烯 --> 高碘酸钠 --> 四氧化锇 --> 丙炔酸乙酯 --> 间苯三酚