CAS 4800-94-6 MFCD00077683-Carbenicillin Disodium Salt 羧苄青霉素钠 TAO{mole}

Carbenicillin Disodium Salt 羧苄青霉素钠

CAS 4800-94-6 MFCD00077683

化学结构图

SMILES: CC1(C)S[C@@H]2[C@H](NC(=O)C(C(=O)O)c3ccccc3)C(=O)N2[C@H]1C(=O)O.[NaH]

化学属性

Mol. Formula	C17 H16 N2 O6 S . 2 Na
Mol. Weight	422.36
Density	1.049
Boiling Point
Melting Point	>190°C (dec.)

别名和识别编码

Chemical Name	Carbenicillin Disodium Salt
CAS Number	4800-94-6
Synonym	######## α-Carboxybenzylpenicillin disodium salt 二钠盐 Anabactyl BRL-2064 CBPC CP-15-639-2 Carbapen Carbecin Carbenicillin Carbenicillin Disodium Carbenicillin Disodium (90%) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
PubChem Substance ID	20933
EC Number	225-360-8
Beilstein Registry Number	5722128
MDL Number	MFCD00077683
Chemical Name Translation	羧苄青霉素钠
Wiswesser Line Notation	T45 ANV ESTJ CMVYR&VO F1 F1 GVO &-NA- 2
LabNetwork Molecule ID	LN00191785
InChI	InChI=1S/C17H18N2O6S.2Na/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8;;/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25);;/q;2*+1/p-2/t9?,10-,11+,14-;;/m1../s1

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分类

{SNA} A - K, Antibacterial, Antibiotic powders, Antibiotics, Antibiotics A to Z, Antibiotics A-F, Antibiotics and Antimycotics, Antibiotics by Application, Biochemicals and Reagents, Cell Culture, Chemical Structure Class, Core Bioreagents, Genetic Marker Selection, Interferes with Cell Wall Synthesis, Mechanism of Action, Molecular Biology, Penicillins and Cephalosporins (beta-Lactams), Plant Biotechnology, Plant Tissue Culture, Reagents and Supplements, Research Essentials, Spectrum of Activity
{SNA} Anal
{SNA} A - K, Antibacterial, Antibiotic powders,
{SNA} Analytical Stan

产品应用

依靠在细菌细胞膜的内层面使转肽酶（transpeptidases）失活抑制细菌细胞壁的合成。类似于青霉素。
抗菌谱: 革兰氏阴性和阳性细菌, 假单胞菌属。
用于选择AMPR转化细胞，并研究青霉素敏感性转肽酶(transpeptidases)对细胞壁生物合成中的作用。

安全信息

GHS Symbol

WGK Germany2

Hazard Codes Xn

Hazard statements

H317 May cause an allergic skin reaction 可能导致皮肤过敏
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves

RTECSON9105000

Precautionary statements

P233 Keep container tightly closed. ?保持容器密闭。
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P284 Wear respiratory protection.? 佩戴呼吸保护装置。
P285 In case of inadequate ventilation wear respiratory protection. 在通风不足的情况下，戴呼吸防护。
P302+P352
P304+P340
P304+P341
P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
P333+P313
P333+P317
P342+P311
P342+P316
P362+P364
P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
P403 Store in a well-ventilated place. 储存在通风良好的地方。
P501 Dispose of contents/container to..… 处理内容物/容器.....

Signal word Danger

Safety Statements

S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
S22 Do not breathe dust 不要吸入粉尘；

Risk Statements

R42/43

Storage condition -20 -20°C -20℃ 2-8℃保存。37 °C 只能保证3天稳定

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >12 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NKRZAZ Chemotherapy (Tokyo).  (Nippon Kagaku Ryoho Gakkai, 2-20-8 Kamiosaki,
   Shinagawa-Ku, Tokyo 141, Japan)  V.1-    1953- Volume(issue)/page/year:
   23,572,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intracerebral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 95500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NKRZAZ Chemotherapy (Tokyo).  (Nippon Kagaku Ryoho Gakkai, 2-20-8 Kamiosaki,
   Shinagawa-Ku, Tokyo 141, Japan)  V.1-    1953- Volume(issue)/page/year:
   17,1111,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 6800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,187,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 7600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,187,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of

其他信息

溶于水。