lycopodine 石松鹼

CAS 466-61-5 MFCD00466615

化学结构图

466-61-5
SMILES:

化学属性

Mol. FormulaC16H25NO
Mol. Weight247.42

别名和识别编码

Chemical NameLycopodine
Chemical Name Translation石松鹼
Chemicalbook IDCB41480614
Synonym Lycopodan-5-one, 15-methyl-, (15R)- (15R)-15-Methyllycopodan-5-one
CAS Number466-61-5
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相关文献及参考

  • [2]. Mandal SK, et al. Lycopodine from Lycopodium clavatum extract inhibits proliferation of HeLa cells through induction of apoptosis via caspase-3 activation. Eur J Pharmacol. 2010 Jan 25;626(2-3):115-22.
  • [1]. Bishayee K, et al. Lycopodine triggers apoptosis by modulating 5-lipoxygenase, and depolarizing mitochondrial membrane potential in androgen sensitive and refractory prostate cancer cells without modulating p53 activity: signaling cascade and drug-DNA interaction. Eur J Pharmacol. 2013 Jan 5;698(1-3):110-21.
  • [1]. Bishayee K, et al. Lycopodine triggers apoptosis by modulating 5-lipoxygenase, and depolarizing mitochondrial membrane potential in androgen sensitive and refractory prostate cancer cells without modulating p53 activity: signaling cascade and drug-DNA interaction. Eur J Pharmacol. 2013 Jan 5;698(1-3):110-21.
  • [2]. Mandal SK, et al. Lycopodine from Lycopodium clavatum extract inhibits proliferation of HeLa cells through induction of a

安全信息

RTECSOL2800600 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 27580 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 34,197,1945

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Lipoxygenase  (脂氧合酶)

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