FTY720 (S)-Phosphate
CAS 402616-26-6 MFCD09840646
化学结构图
SMILES: CCCCCCCCC1=CC=C(CC[C@@](N)(COP(O)(O)=O)CO)C=C1
化学属性
| Mol. Formula | C19H34NO5P |
|---|---|
| Mol. Weight | 387.4507 |
别名和识别编码
| Chemical Name | FTY720 (S)-Phosphate |
|---|---|
| CAS Number | 402616-26-6 |
| Synonym | 2-(S)-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol Mono(dihydrogen phosphate) Ester (S)-FTY720-P |
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分类
- Inhibitors
- Metabolites & Impurities
产品应用
- FTY720 is a sphingosine 1-phosphate receptor modular, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration. FTY720 Phosphate is the active metabolite of FTY720-
相关文献及参考
- [2]. Lingling Jia, et al. Clostridium butyricum CGMCC0313.1 Protects against Autoimmune Diabetes by Modulating Intestinal Immune Homeostasis and Inducing Pancreatic Regulatory T Cells. Front Immunol. 2017 Oct 19;8:1345.
- Brinkmann, V., et al.: J. Biol. Chem., 277, 21453 (2002),
- Chiba, K., et al.: J. Immunol., 160, 5037 (1998),
- [1]. Wang L, et al. FTY720 (s)-phosphonate preserves sphingosine 1-phosphate receptor 1 expression and exhibits superior barrier protection to FTY720 in acute lung injury. Crit Care Med. 2014 Mar;42(3):e189-99.
- [1]. Wang L, et al. FTY720 (s)-phosphonate preserves sphingosine 1-phosphate receptor 1 expression and exhibits superior barrier protection to FTY720 in acute lung injury. Crit Care Med. 2014 Mar;42(3):e189-99.
- [2]. Lingling Jia, et al. Clostridium butyricum CGMCC0313.1 Protects against Autoimmune Diabetes by Modulating Intestinal Immune Homeostasis and Inducing Pancreatic Regulatory T Cells. Front Immunol. 201
