BVT-948 化合物BVT948
CAS 39674-97-0 MFCD00616487
化学结构图
SMILES: CC1(C)C2=C(O)C(=O)C3C=CC=CC=3C2=NC1=O
化学属性
| Mol. Formula | C14H11NO3 |
|---|---|
| Mol. Weight | 241.24 |
别名和识别编码
| Chemical Name | BVT-948 |
|---|---|
| Synonym | 4-Hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione |
| MDL Number | MFCD00616487 |
| PubChem Substance ID | 24724422 |
| CAS Number | 39674-97-0 |
| Chemical Name Translation | 化合物BVT948 |
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分类
- B, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Tyrosine Phosphatase (TP), Tyrosine Phosphatase Biology, Tyros
- {SNA} B, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Tyrosine Phosphatase (TP), Tyrosine Phosphatase Biology, Tyrosine Phosphatase Inhibitors
- {SNA} B, Bioactive Small Molecule Alphabetical Index, Kinase/Phosphatase Biology, Tyrosine Phosphatase (TP), Tyrosine Phosphatase Biology, Tyrosine Phosphatase Inhibitors, 生物活性小分子, 细胞信号转导和神经科学,
相关文献及参考
- [2]. Blum G, et al. Small-molecule inhibitors of SETD8 with cellular activity. ACS Chem Biol. 2014 Nov 21;9(11):2471-8.
- [3]. Hwang BM, et al. Protein tyrosine phosphatase controls breast cancer invasion through the expression of matrix metalloproteinase-9. BMB Rep. 2013 Nov;46(11):533-8.
- Liljebris, C., et al., Oxidation of Protein Tyrosine Phosphatases as a Pharmaceutical Mechanism of Action: A Study Using 4-Hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione. J. Pharmacol. Exp. Ther. 309 , 711-719, (2004)
- [1]. Liljebris C, et al. Oxidation of protein tyrosine phosphatases as a pharmaceutical mechanism of action: a study using 4-hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione. J Pharmacol Exp Ther. 2004 May;309(2):711
- [1]. Liljebris C, et al. Oxidation of protein tyrosine phosphatases as a pharmaceutical mechanism of action: a study using 4-hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione. J Pharmacol Exp Ther. 2004 May;309(2):711-9.
安全信息
GHS Symbol
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- H317 May cause an allergic skin reaction 可能导致皮肤过敏
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
- R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
