Fluorometholone Acetate 氟米龙醋酸酯
CAS 3801-06-7 MFCD00866062
化学结构图
SMILES: CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C
化学属性
| Mol. Formula | C24H31FO5 |
|---|---|
| Mol. Weight | 419 |
| Solubility | DMSO 84 mg/mL Water <1 mg/mL Ethanol <1 mg/mL |
别名和识别编码
| Chemical Name | Fluorometholone Acetate |
|---|---|
| CAS Number | 3801-06-7 |
| Synonym | Pregna-1,4-diene-3,20-dione, 17-(acetyloxy)-9-fluoro-11-hydroxy-6-methyl-, (6α,11β)- (6?,11?)-17-(Acetyloxy)-9-fluoro-11-hydroxy-6-methylpregna-1,4-diene-3,20-dione Fluorometholone acetate; 9-Fluoro-11b,17-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione 17-acetate 氟米龙醋酸酯 |
| EC Number | 223-270-3 |
| Chemical Name Translation | 氟米龙醋酸酯 |
| LabNetwork Molecule ID | LN01299442 |
| PubChem Substance ID | 240767 |
| InChI | InChI=1S/C24H31FO5/c1-13-10-19-17-7-9-23(14(2)26,30-15(3)27)22(17,5)12-20(29)24(19,25)21(4)8-6-16(28)11-18(13)21/h6,8,11,13,17,19-20,29H,7,9-10,12H2,1-5H3/t13-,17-,19-,20-,21-,22-,23-,24-/m0/s1 |
| MDL Number |
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分类
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Steroids
产品应用
- A glucocorticoid and anti-inflammatory.
相关文献及参考
- [2]. Zuhal Alım, et al. Some Anti-Inflammatory Agents Inhibit Esterase Activities of Human Carbonic Anhydrase Isoforms I and II: An In Vitro Study. Chem Biol Drug Des. 2015 Oct;86(4):857-63.
- [3]. H M Leibowitz, et al. Fluoro metholone acetate: clinical evaluation in the treatment of external ocular inflammation. Ann Ophthalmol. 1984 Dec;16(12):1110-5.
- Kupferman, A., et al.: Arch. Ophthalmol., 100, 640 (1982),
- Tokunaga, H., et al.: Chem. Pharm. Bull., 32, 4012 (1984),
- [1]. A Kupferman, et al. Fluorometholone acetate. A new ophthalmic derivative of fluorometholone. Arch Ophthalmol. 1982 Apr;100(4):640-1.
- [1]. A Kupferman, et al. Fluorometholone acetate. A new ophthalmic derivative of fluorometholone. Arch Ophthalmol. 1982 Apr;100(4):640-1.
- [2]. Zuhal Alım, et al. Some Anti-Inflammatory Agents Inhibit Esterase Activities of Human Carbonic Anhydrase Isoforms I and II: An In Vitro Study. Chem Biol Drug Des. 2015 Oct;86(4):857-63.
- {MC
安全信息
其他信息
- Fluorometholone Acetate 是一种合成的皮质类固醇, 用于治疗类固醇反应性眼睛炎症。
