LHRH

CAS 35263-73-1 MFCD00167539

化学结构图

35263-73-1
SMILES: CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CNC2C=CC=CC1=2)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)NCC(O)=O

化学属性

Mol. FormulaC55H74N16O14
Mol. Weight1183.27

别名和识别编码

Chemical NameLuteinizing hormone releasing hormone
Synonym GnRH Gonadotropin-releasing hormone LH-RH [Gly-OH10]-LH-RH pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly LH-RH LH-RH [Gly-OH10]-LH-RH pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly [Gly-OH10]-LH-RH pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly
MDL NumberMFCD00167539
PubChem Substance ID24896489
CAS Number35263-73-1
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分类

  • Cell Biology, Cell Signaling and Neuroscience, LH-RH, Peptides and Proteins, Peptides for Cell Biology, Releasing Factors
  • {SNA} Cell Biology, Cell Signaling and Neuroscience, LH-RH, Peptides and Proteins, Peptides for Cell Biology, Releasing Factors
  • {SNA} LH-RH, Peptides and Proteins, Peptides for Cell Biology, Releasing Factors, 细胞信号转导和神经科学, 细胞生物学

相关文献及参考

  • Schally, A.V. Science 202 , 18, (1978) 摘要
  • Rivier, J.E. and Vales, W.W. Life Sci. 23 , 869, (1978) 摘要
  • Hirdes, W., et al., Gonadotropin-Releasing Hormone Inhibits Ether-à-Go-Go-Related Gene K+ Currents In Mouse Gonadotropes Endocrinol. Relat. Cancer 151 , 1079-1088, (2010)

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P308+P313
  • P201 Obtain special instructions before use. 使用前获取专门指示。
Signal word Danger
Hazard statements
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
Hazard Codes T
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S22 Do not breathe dust 不要吸入粉尘;
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
Risk Statements
  • R60 May impair fertility 可能降低生殖能力

系列性分类


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