Coptisine 黄连碱, 来源于黄连
CAS 3486-66-6 MFCD03792689
化学结构图
SMILES: c1c2c(cc3c1OCO3)-c1cc3ccc4c(c3c[n+]1CC2)OCO4
化学属性
| Mol. Formula | C19H14NO4 |
|---|---|
| Mol. Weight | 320 |
别名和识别编码
| Chemical Name | Coptisine |
|---|---|
| Synonym | 6,7-Dihydrobis[1,3]benzodioxolo[5,6-a:4',5'-g]quinolizinium 7,8,13,13a-tetradehydro-2,3-9,10-bis(methylenedioxy)berbinium Bis(methylenedioxy)protoberberine chloride, Coptisine chloride coptisine coptisine chloride 小檗碱 |
| CAS Number | 3486-66-6 |
| Chemical Name Translation | 黄连碱, 来源于黄连 |
| LabNetwork Molecule ID | LN01343175 |
| PubChem Substance ID | 72322 |
| InChI | InChI=1S/C19H14NO4/c1-2-16-19(24-10-21-16)14-8-20-4-3-12-6-17-18(23-9-22-17)7-13(12)15(20)5-11(1)14/h1-2,5-8H,3-4,9-10H2/q+1 |
| MDL Number | MFCD03792689 |
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相关文献及参考
- [2]. He K, et al. The safety and anti-hypercholesterolemic effect of coptisine in Syrian golden hamsters. Lipids. 2015 Feb;50(2):185-94.
- [3]. Rao PC, et al. Coptisine-induced cell cycle arrest at G2/M phase and reactive oxygen species-dependent mitochondria-mediated apoptosis in non-small-cell lung cancer A549 cells. Tumour Biol. 2017 Mar;39(3):1010428317694565.
- [1]. Yu D, et al. The IDO inhibitor coptisine ameliorates cognitive impairment in a mouse model of Alzheimer's disease. J Alzheimers Dis. 2015;43(1):291-302.
- [1]. Yu D, et al. The IDO inhibitor coptisine ameliorates cognitive impairment in a mouse model of Alzheimer's disease. J Alzheimers Dis. 2015;43(1):291-302.
- [2]. He K, et al. The safety and anti-hypercholesterolemic effect of coptisine in Syrian golden hamsters. Lipids. 2015 Feb;50(2):185-94.
- [3]. Rao PC, et al. Coptisine-induced cell cycle arrest at G2/M phase and reactive oxygen species-dependent mitochondria-mediated a
安全信息
GHS Symbol
- P301+P312+P330
