3-Phenyl-1H-Benzofuro[3,2-c]Pyrazole 3-苯基-1H-苯并呋喃并[3,2-c]吡唑
CAS 34823-86-4 MFCD01416326
化学结构图
SMILES: c1ccc(-c2n[nH]c3c2oc2ccccc23)cc1
化学属性
| Mol. Formula | C15H10N2O |
|---|---|
| Mol. Weight | 234.25 |
| Appearance | Solid powder |
| Solubility | Soluble in DMSO, not in water |
别名和识别编码
| Chemical Name | 3-Phenyl-1H-Benzofuro[3,2-c]Pyrazole |
|---|---|
| Formula | C15H10N2O |
| Synonym | GTP14564; GTP 14564; GTP-14564 |
| IUPAC Name | 3-phenyl-1H-benzofuro[3,2-c]pyrazole |
| InChIKey | DZQLVVLATXPWBK-UHFFFAOYSA-N |
| InChI | InChI=1S/C15H10N2O/c1-2-6-10(7-3-1)13-15-14(17-16-13)11-8-4-5-9-12(11)18-15/h1-9H,(H,16,17) |
| Canonical SMILES | C12=C(OC3=CC=CC=C32)C(C4=CC=CC=C4)=NN1 |
| Chemical Name Translation | 3-苯基-1H-苯并呋喃并[3,2-c]吡唑 |
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产品应用
- GTP-14564 is a specific kinase inhibitor for ITD-FLT3. GTP-14564 inhibited the growth of interleukin-3-independent Ba/F3 expressing ITD-FLT3 at 1 microM, whereas a 30-fold higher concentration of GTP-14564 was required to inhibit FLT3 ligand-dependent growth of Ba/F3 expressing wild type FLT3 (wt-FLT3).
