5-Phenylpyridin-2-amine 2-氨基-5-苯基吡啶

CAS 33421-40-8 MFCD01692452

化学结构图

33421-40-8
SMILES: Nc1ccc(-c2ccccc2)cn1

化学属性

Mol. FormulaC11H10N2
Mol. Weight170
Melting Point134-138
TSCANo

别名和识别编码

Chemical Name5-Phenylpyridin-2-amine
CAS Number33421-40-8
Alfabeta NameAMINOPHENYLPYRIDINE 25---
MDL NumberMFCD01692452
Synonym 2-Amino-5-phenylpyridine 5-Phenyl-2-pyridinamine 5-Phenylpyridin-2-ylamine Phe-P-1
Reaxys-RN120219
PubChem Substance ID87563086
Chemical Name Translation2-氨基-5-苯基吡啶
Wiswesser Line NotationT6NJ BZ FR
Beilstein Registry Number120219
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分类

  • Building Blocks, C11, Chemical Synthesis, Heterocyclic Building Blocks, Pyridines

产品应用

  • A product from the pyrolysis of phenylalanine.

相关文献及参考

  • [2]. Stavenuiter JF, et al. Syntheses of 5-phenyl-2-pyridinamine, a possibly carcinogenic pyrolysis product of phenylalanine, and some of its putative metabolites. Carcinogenesis. 1985 Jan;6(1):13-9.
  • Kim, D., et al.: Bioorg. Med. Chem. Lett., 15, 2129 (2005),
  • [1]. Dooley KL, et al. Comparative carcinogenicity of the food pyrolysis product, 2-amino-5-phenylpyridine, and the known human carcinogen, 4-aminobiphenyl, in the neonatal B6C3F1 mouse. Cancer Lett. 1988 Jul;41(1):99-103.
  • [1]. Dooley KL, et al. Comparative carcinogenicity of the food pyrolysis product, 2-amino-5-phenylpyridine, and the known human carcinogen, 4-aminobiphenyl, in the neonatal B6C3F1 mouse. Cancer Lett. 1988 Jul;41(1):99-103.
  • [2]. Stavenuiter JF, et al. Syntheses of 5-phenyl-2-pyridinamine, a possibly carcinogenic pyrolysis product of phenylalanine, and some of its putative metabolites. Carcinogenesis. 1985 Jan;6(1):13-9.

安全信息

RTECSUS2145000
Signal word Danger
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H301 Toxic if swallowed 吞食有毒
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
GHS Symbol
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 ug/plate
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 26,611,1978

WGK Germany3
Hazard Codes Xn

系列性分类


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