CAS 321-14-2 MFCD00002457-5-Chlorosalicylic Acid 5-氯水杨酸 TAO{mole}

5-Chlorosalicylic Acid 5-氯水杨酸

CAS 321-14-2 MFCD00002457

化学结构图

SMILES: O=C(O)c1cc(Cl)ccc1O

化学属性

Mol. Formula	C7H5ClO3
Mol. Weight	172.56
Density	1.536
Melting Point	171-176°C
TSCA	Yes
Solubility	1 G/L (20 ºC)
Appearance	白色结晶性粉末。熔点173-174℃（172℃，174-176℃）。溶于热水，难溶于冷水，易溶于乙醇、乙醚、苯、氯仿和乙酸。与氯化铁作用呈红紫色。
Boiling Point	320.5°C at 760 mmHg

别名和识别编码

Chemical Name	5-Chlorosalicylic Acid
Synonym	5-Chloro-2-hydroxybenzoic acid {LY} 5-Chloro-2-hydroxybenzoic acid {} {LY} 5-Chloro-2-hydroxybenzoic acid {} {} {LY} 5-Chloro-2-hydroxybenzoic acid {} {} {} {LY} 5-Chloro-2-hydroxybenzoic acid {} {} {} {} {LY} 5-Chloro-2-hydroxybenzoic acid {} {} {} {} {} {LY} 5-Chloro-2-hydroxybenzoic acid {} {} {} {} {} {} {LY} 5-Chloro-2-hydroxybenzoic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 5-Chloro-2-hydroxybenzoic acid {} {} {} {} {} {} {} {} {LY} 5-Chloro-2-hydroxybenzoic acid {} {} {} {} {} {} {} {} {} {LY} 5-Chloro-2-hydroxybenzoic acid {} {} {} {} {} {} {} {} {} {} {LY} 5-Chloro-2-hydroxybenzoic acid {} {} {} {} {} {} {} {} {} {} {} {LY} 5-Chloro-2-hydroxybenzoic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 5-Chloro-2-hydroxybenzoic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 5-Chloro-2-hydroxybenzoic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
CAS Number	321-14-2
EC Number	206-283-9
Beilstein Registry Number	2046665
MDL Number	MFCD00002457
PubChem Substance ID	87565441
Alfabeta Name	CHLOROHYDROXYBENZOICACID 52---
Chemical Name Translation	5-氯水杨酸
Reaxys-RN	2046665
Wiswesser Line Notation	QVR BQ EG
LabNetwork Molecule ID	LN00177294
InChI	InChI=1S/C7H5ClO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,(H,10,11)
Canonical SMILES	O=C(O)C1=CC(Cl)=CC=C1O

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

染料、医药的中间体。

安全信息

Signal word Danger

GHS Symbol

WGK Germany3

Safety Statements

S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S36 Wear suitable protective clothing 穿戴适当的防护服；
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；

Risk Statements

R22 Harmful if swallowed 吞咽有害
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性

Precautionary statements

P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P301+P310
P301+P310+P330
P302+P352+P332+P313+P362+P364
P305+P351+P338
P305+P351+P338+P337+P313
P332+P313
P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
P405 Store locked up. 上锁保管。
P501 Dispose of contents/container to..… 处理内容物/容器.....

Hazard statements

H301 Toxic if swallowed 吞食有毒
H315 Causes skin irritation 会刺激皮肤
H319 Causes serious eye irritation 严重刺激眼睛

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves

RTECSVO2080000

Packing GroupIII

UN Number 2811 UN 2811 6.1/PG 3

Hazard Codes 6.1 Xn

Warnings IRRITANT

Hazard Class6.1

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PHMGBN Pharmacology: International Journal of Experimental and Clinical
   Pharmacology.  (S. Karger AG, Postfach CH-4009 Basel, Switzerland)  V.1-
   1968-  Volume(issue)/page/year: 9,164,1973

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CBCCT* "Summary Tables of Biological Tests," National Research Council
   Chemical-Biological Coordination Center.  (National Academy of Science
   Library, 2101 Constitution Ave., NW, Washington, DC 20418)
   Volume(issue)/page/year: 7,792,1955

Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {}

其他信息

5-氯代水杨酸价格(试剂级):更新日期产品编号产品名称包装价格 2011/08/23 xw010185 5-氯水杨酸;5-氯-2-羟基苯甲酸 100g 85元 2011/04/16 C0287 5-氯水杨酸 5-Chlorosalicylic Acid 25G 158元 2011/04/16 C0287 5-氯水杨酸 5-Chlorosalicylic Acid 500G 873元
用途二:染料、医药的中间体。
白色结晶性。溶于热水，难溶于冷水，易溶于乙醇、乙醚、苯、氯仿和乙酸。与氯化铁作用呈红紫色。水溶性1 g/L (20°C)。
海关编码:29182990
MOL 文件:321-14-2.mol
Sigma Aldrich:321-14-2(sigmaaldrich)
方法一:将氯苯加入搪瓷锅蒸去水分至0.03%以下，投入水杨酸，在110±2℃均匀通氯至预定量。取样观察冷至30℃的析出物，过滤，测熔点，以167-175℃为合格，即得5-氯水杨酸的氯苯溶液。如果氯化反应在日光灯照射下进行，则在55-80℃能氯至理论量，取样检测合格后，排除剩余氯，冷却，过滤，用氯苯洗涤，干燥，即得成品。
图谱信息:5-氯代水杨酸(321-14-2)Raman光谱 5-氯代水杨酸(321-14-2)红外图谱(IR1) 5-氯代水杨酸(321-14-2)核磁图( 13 CNMR) 5-氯代水杨酸(321-14-2)红外图谱(IR2) 5-氯代水杨酸(321-14-2)质谱(MS)
Alfa Aesar:5-氯水杨酸,99% 5-Chlorosalicylic acid, 99%(321-14-2)
下游产品:溴替尼持 --> 5-氯-2-甲氧基苯甲酰氯 --> 4-[2-(5-氯-2-甲氧基苯甲酰氨基)乙基]苯磺酰胺 --> 5-氯-2-甲氧基苯甲酸 --> 5-氯-2-羟基苯甲酸甲酯 --> 氯硝柳胺
MSDS 信息:5-Chloro-2-hydroxybenzoic acid(321-14-2).msds
Acros Organics:5-氯水杨酸 5-Chlorosalicylic acid, 98%(321-14-2)
用途一:用作农药、医药、染料中间体
上游原料:氯 --> 水杨酸
TCI Shanghai:5-氯代水杨酸 5-Chlorosalicylic Acid,>;98.0%(GC)(T)(321-14-2)