Sodium 2-iodoacetate 2-碘乙酸钠
CAS 305-53-3 MFCD00002686
信息真实价格透明
资金保障
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
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分类
- {SNA} Biochemicals and Reagents, D to K, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Glutamyltranspeptidase, gamma-, Glyceraldehyde-3-phosphate dehydrogenase, P to Q, Phospholipase C, phosphatidylinositol-specific, Protein Modification, Protein Structural Analysis, Reagents for cysteine modification,
- {SNA} Bromelain,
产品应用
- 用于蛋白质中修饰胱氨酸残基的试剂
相关文献及参考
- Guzman, R.E., et al., Mono-Iodoacetate-Induced Histologic Changes in Subchondral Bone and Articular Cartilage of Rat Femorotibial Joints: An Animal Model of Osteoarthritis Toxicol. Pathol. 31 , 619-24, (2003) 摘要
- Beilstein: 2,222
- Beil. 2 ,222
- Inglis, A.S., Single hydrolysis method for all amino acids, including cysteine and tryptophan. Meth. Enzymol. 91 , 26-36, (1983) 摘要
- Kalff, K.M., et al., Pre-treatment with capsaicin in a rat osteoarthritis model reduces the symptoms of pain and bone damage induced by monosodium iodoacetate Eur. J. Pharmacol. 641 , 108-113, (2010) 摘要
安全信息
GHS Symbol
- H315 Causes skin irritation 会刺激皮肤
- H318 Causes serious eye damage 严重伤害眼睛
- H301 Toxic if swallowed 吞食有毒
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P310
- P305+P351+P338
- S22 Do not breathe dust 不要吸入粉尘;
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S39 Wear eye/face protection 戴眼睛/面孔保护装置;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- R25 Toxic if swallowed 吞咽有毒
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
- R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 83 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 86,336,1946
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 75 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 30 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 17,814,1965
TYPE OF TEST : DNA inhibition TEST SYSTEM : Human Lymphocyte DOSE/DURATION : 10 mmol/L REFERENCE : STBIBN Studia Biophysica. (Akademie-Verlag GmbH, Postfach 1233, Berlin DDR-1086, Ger. Dem. Rep.) V.1- 1966- Volume(issue)/page/year: 50,97,1975
TYPE OF TEST : DNA damage TEST SYSTEM : Rodent - rat Liver DOSE/DURATION : 10 umol/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 368,59,1996
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE : 500 mg/kg SEX/DURATION : female 8-12 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - live birth index (measured after birth) Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) REFERENCE : TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1980- Volume(issue)/page/year: 6,361,1986
其他信息
- 图谱信息:碘代乙酸钠盐(305-53-3)红外图谱(IR1)
- 用途一:用于制药工业
- 用途二:用于蛋白质中修饰胱氨酸残基的试剂
- Sigma Aldrich:305-53-3(sigmaaldrich)
- F:3-8-10
- Acros Organics:碘代乙酸钠盐 Iodoacetic acid, sodium salt, 99%(305-53-3)
- 外观性质:白色或浅黄色结晶。有吸潮性。溶于水,不溶于醇、醚和丙酮。熔点: 208-210 °C
- MOL 文件:305-53-3.mol
- 碘代乙酸钠盐价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/06/21 170970250 碘代乙酸钠盐 Iodoacetic acid, sodium salt 99% 25 GR 1621元 2010/06/21 170971000 碘代乙酸钠盐 Iodoacetic acid, sodium salt 99% 100 GR 4722元
- 有吸潮性。溶于水,不溶于醇、醚和丙酮。