CAS 294-93-9 MFCD00005103-12-Crown-4 12-冠醚-4 TAO{mole}

12-Crown-4 12-冠醚-4

CAS 294-93-9 MFCD00005103

化学结构图

SMILES: C1COCCOCCOCCO1

化学属性

Mol. Formula	C8H16O4
Mol. Weight	176.21
Density	1.089
Refractive index	n20/D 1.463(lit.)
Flash Point	>109°(228°F)
TSCA	Yes
Boiling Point	61-70 °C at 0.5 mmHg
Melting Point	16 °C
Solubility	MISCIBLE
Stability	对空气敏感;对光敏感

别名和识别编码

Chemical Name	12-Crown-4
MDL Number	MFCD00005103
Synonym	12-Crown-4 {LY} 12-Crown-4 {} {LY} 12-Crown-4 {} {} {LY} 12-Crown-4 {} {} {} {LY} 12-Crown-4 {} {} {} {} {LY} 12-Crown-4 {} {} {} {} {} {LY} 12-Crown-4 {} {} {} {} {} {} {LY} 12-Crown-4 {} {} {} {} {} {} {} {LY} 12-Crown-4 {} {} {} {} {} {} {} {} {LY} 12-Crown-4 {} {} {} {} {} {} {} {} {} {LY} 12-Crown-4 {} {} {} {} {} {} {} {} {} {} {LY} 12-Crown-4 {} {} {} {} {} {} {} {} {} {} {} {LY} 12-Crown-4 {} {} {} {} {} {} {} {} {} {} {} {} {LY} 12-Crown-4 {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 12-Crown-4 {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 12-Crown-4 {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 12-Crown-4 {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 12-Crown-4 {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 12-Crown-4 {} {} {} {} {} {} {} {} {}
EC Number	206-036-5
CAS Number	294-93-9
Beilstein Registry Number	1363064
PubChem Substance ID	9269
Reaxys-RN	1363064
Chemical Name Translation	12-冠醚-4
Wiswesser Line Notation	T-12-O DO GO JOTJ
LabNetwork Molecule ID	LN01363684
InChI	InChI=1S/C8H16O4/c1-2-10-5-6-12-8-7-11-4-3-9-1/h1-8H2
Canonical SMILES	C1COCCOCCOCCO1

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品牌质保精细包装现货库存一流品牌服务

产品应用

An aprotic "solvent" for alkali metals, the sodium solution is a strong reducing agent

安全信息

RTECSXF0550000

UN Number 2810 UN 2810 UN2810

Risk Statements

R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
R26 Very toxic by inhalation 吸入极毒
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

Safety Statements

S20 When using do not eat or drink 使用时，不得进食，饮水；
S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾；
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
S36 Wear suitable protective clothing 穿戴适当的防护服；
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
S4 Keep away from living quarters 远离生活区；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
S9 Keep container in a well-ventilated place 保持容器在通风良好的场所；

Storage condition Air Sensitive Light & Air Sensitive & Hygroscopic 密封保存。对空气敏感，密封保存。

GHS Symbol

WGK Germany3

Hazard statements

H303 May be harmfully swallowed 吞食可能有害
H319 Causes serious eye irritation 严重刺激眼睛
H330 Fatal if inhaled 吸入致命

Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

Precautionary statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P284 Wear respiratory protection.? 佩戴呼吸保护装置。
P304+P340
P304+P340+P310
P305+P351+P338
P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
P320 Specific treatment is urgent (see … on this label). 紧急具体治疗（见本标签上的）。
P332+P313
P337+P313
P403+P233
P405 Store locked up. 上锁保管。
P501 Dispose of contents/container to..… 处理内容物/容器.....

Signal word Danger

Packing GroupIII

Hazard Codes 6.1 T+ T+,Xn Xn

Hazard Class6.1

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3150 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   44,263,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1290 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   DCTODJ Drug and Chemical Toxicology.  (Marcel Dekker, 270 Madison Ave., New
   York, NY 10016) V.1-    1977/78-  Volume(issue)/page/year: 8,451,1985

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2830 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
REFERENCE :
   DCTODJ Drug and Chemical Toxicology.  (Marcel Dekker, 270 Madison Ave., New
   York, NY 10016) V.1-    1977/78-  Volume(issue)/page/year: 1,339,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 4530 uL/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0536186

TYPE OF TEST

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 500 ppb/7H
SEX/DURATION            : male 15 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   27,342,1974

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1 ppm/7H
SEX/DURATION            : male 15 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
   accessory glands
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   27,342,1974

其他信息

Alfa Aesar:12-冠-4,98% 12-Crown-4, 98%(294-93-9)
MSDS 信息:1,4,7,10-Tetraoxacyclododecane(294-93-9).msds
Sigma Aldrich:294-93-9(sigmaaldrich)
Acros Organics:12-冠醚-4 12-Crown-4, 97%(294-93-9)
图谱信息:12-冠醚-4(294-93-9)质谱(MS) 12-冠醚-4(294-93-9)Raman光谱 12-冠醚-4(294-93-9)核磁图( 13 CNMR) 12-冠醚-4(294-93-9)核磁图( 1 HNMR) 12-冠醚-4(294-93-9)红外图谱(IR1)
敏感性:Air Sensitive
MOL 文件:294-93-9.mol
海关编码:29329995
TCI Shanghai:12-冠4-醚 12-Crown 4-Ether,>;95.0%(GC)(294-93-9)
F:3-9-23
12-Crown-4 is a Phase transfer catalyst, complexing-agent for lithium. Aprotic "solvent" for alkali metals, the sodium solution is a strong reducing agent.
12-冠醚-4价格(试剂级):更新日期产品编号产品名称包装价格 2014/06/02 C0858 12-冠4-醚 12-Crown 4-Ether 1ML 293元 2014/06/02 C0858 12-冠4-醚 12-Crown 4-Ether 5ML 865元 2010/06/21 187020050 12-冠醚-4 12-Crown-4 97% 5 GR 942元