2-Chlorobenzenesulfonyl Chloride 2-氯苯磺酰氯

CAS 2905-23-9 MFCD00051520

化学结构图

2905-23-9
SMILES: O=S(=O)(Cl)c1ccccc1Cl

化学属性

Mol. FormulaC6H4Cl2O2S
Mol. Weight211
Boiling Point150-152
Melting Point26-28°
Density1.548
Refractive index1.5750 to 1.5790
Flash Point60°C(lit.)
TSCAYes

别名和识别编码

Chemical Name2-Chlorobenzenesulfonyl Chloride
CAS Number2905-23-9
Alfabeta NameCHLOROBENZENESULFONYLCHLORIDE 2-
MDL NumberMFCD00051520
EC Number220-807-3
Beilstein Registry Number974321
PubChem Substance ID76187
Synonym 2-Chlorobenxenesulfonyl Chloride BUTTPARK 37\11-76 2-chloro-benzenesulfonylchlorid 2-Chlorobenzenesulfonyl chloride 2-CHLOROBENZENESULPHONYL CHLORIDE 2-CHLOROBENZENESULFONYL CHLORIDE 2-Chlorobenzene-1-sulfonyl chloride o-Chlorobenzenesulfonyl chloride o-Chlorobenzenesulfochloride 2-CHLOROBENZENE-1-SULFONYL CHLORIDE Benzenesulfonyl chloride, o-chloro- 2-Chlrorbenzolsulfonoic acid chloranehydride Benzenesulfonyl chloride, 2-chloro- 邻氯苯磺酰氯 2-氯苯磺酰氯 o-chloro-benzenesulfonylchlorid o-chlorobenzenesulfonyl chloride o-chlorobenzenesulfochloride 2-Chlorobenzenesulfonic acid chloride
Chemical Name Translation2-氯苯磺酰氯
Reaxys-RN974321
InChIKeyKMVZDSQHLDGKGV-UHFFFAOYSA-N
LabNetwork Molecule IDLN00010946
InChIInChI=1S/C6H4Cl2O2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H
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分类

  • {SNA} Building Blocks, Chemical Synthesis, Organic Building Blocks, Sulfonyl Halides, Sulfur Compounds

安全信息

Warnings MOISTURE SENSITIVE, CORROSIVE
Signal word
GHS Symbol
WGK Germany2
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Risk Statements
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P370+P378
  • P303+P361+P353
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P305+P351+P338
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338+P310
  • P304+P340
RTECSDB8925500
Packing GroupII
UN Number
Storage condition Moisture Sensitive
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard Codes C
Hazard Class8/3
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2750 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 54(4),72,1989

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 7500 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 54(4),72,1989

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 7732 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFER

TYPE OF TEST            : LC - Lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >2 gm/m3/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 54(4),72,1989

其他信息

  • 急性毒性:口服-大鼠 LD50: 7500 毫克/公斤; 口服-小鼠 LD50: 2750 毫克/公斤
  • 可燃性危险特性:热分解排出有毒氮氧化物, 硫氧化物烟雾
  • 方法一:将邻氯苯胺、浓盐酸、冰乙酸混合搅拌,降温至0℃以下,滴加亚硝酸钠溶液,重氮化反应后,加入含氯化铜的SO2冰乙酸溶液,反应1.5h。然后进行冰析,用乙醚提取。提取液用碱水洗至中性,干燥,蒸去乙醚,最后减压蒸馏收集96-98℃(0.133kPa)馏分,得邻氯苯磺酰氯。
  • 类别:有毒物质
  • 灭火剂:水,二氧化碳, 泡沫, 干粉
  • Sigma Aldrich:2905-23-9(sigmaaldrich)
  • 储运特性:库房低温通风干燥
  • Alfa Aesar:2-氯苯磺酰氯,98% 2-Chlorobenzenesulfonyl chloride, 98%(2905-23-9)
  • 毒性分级:中毒
  • 2-氯苯磺酰氯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/06/21 357460050 2-氯苯磺酰氯 2-Chlorobenzenesulfonyl chloride 98% 5 GR 954元 2010/06/21 357460010 2-氯苯磺酰氯 2-Chlorobenzenesulfonyl chloride 98% 1 GR 336元 2010/06/21 RF02645DA 2-氯苯磺酰氯 2-chlorobenzene-1-sulfonyl chloride 1 GR 270元
  • 用途一:农药中间体。
  • 下游产品:氯磺隆 --> 邻氯苯磺酰胺
  • Hazard Note:Corrosive
  • Acros Organics:2-氯苯磺酰氯 2-Chlorobenzenesulfonyl chloride, 98%(2905-23-9)
  • 上游原料:2-氯苯胺
  • MOL 文件:2905-23-9.mol
  • 敏感性:Moisture Sensitive
  • MSDS 信息:2-Chlorobenzene-1-sulfonyl chloride(2905-23-9).msds

系列性分类


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