CAS 2426-08-6 MFCD00005145-Butyl glycidyl ether 丁基缩水甘油醚 TAO{mole}

Butyl glycidyl ether 丁基缩水甘油醚

CAS 2426-08-6 MFCD00005145

化学结构图

SMILES: CCCCOCC1CO1

化学属性

Mol. Formula	C7H14O2
Mol. Weight	130.18
Refractive index	1.4170 to 1.4200
Boiling Point	164-166
Density	0.91
Flash Point	59°C(lit.)
TSCA	Yes
Solubility	2 G/100 ML

别名和识别编码

Chemical Name	Butyl glycidyl ether
Synonym	2-(Butoxymethyl)oxirane {LY} 2-(Butoxymethyl)oxirane {} {LY} 2-(Butoxymethyl)oxirane {} {} {LY} 2-(Butoxymethyl)oxirane {} {} {} {LY} 2-(Butoxymethyl)oxirane {} {} {} {} {LY} 2-(Butoxymethyl)oxirane {} {} {} {} {} {LY} 2-(Butoxymethyl)oxirane {} {} {} {} {} {} {LY} 2-(Butoxymethyl)oxirane {} {} {} {} {} {} {} {LY} 2-(Butoxymethyl)oxirane {} {} {} {} {} {} {} {} {LY} 2-(Butoxymethyl)oxirane {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-(Butoxymethyl)oxirane {} {} {} {} {} {} {} {} {} {} {LY} 2-(Butoxymethyl)oxirane {} {} {} {} {} {} {} {} {} {} {} {LY} 2-(Butoxymethyl)oxirane {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-(Butoxymethyl)oxirane {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-(Butoxymethyl)oxirane {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-(Butoxymethyl)oxirane {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-(Butoxymethyl)oxirane {} {} {} {} {} {} {} {}
CAS Number	2426-08-6
PubChem Substance ID	17049
EC Number	219-376-4
Beilstein Registry Number	103668
MDL Number	MFCD00005145
Reaxys-RN	103668
Chemical Name Translation	丁基缩水甘油醚
Wiswesser Line Notation	T3OTJ B1O4
LabNetwork Molecule ID	LN00224805
InChI	InChI=1S/C7H14O2/c1-2-3-4-8-5-7-6-9-7/h7H,2-6H2,1H3
Canonical SMILES	CCCCOCC1CO1

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安全信息

GHS Symbol

WGK Germany3

Hazard Codes T Xn

Hazard statements

H226 Flammable liquid and vapour 易燃液体和蒸气
H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
H331 Toxic if inhaled 吸入中毒
H302 Harmful if swallowed 吞食有害
H335 May cause respiratory irritation 可能导致呼吸道刺激
H350 May cause cancer 可能致癌
H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。
H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
H317 May cause an allergic skin reaction 可能导致皮肤过敏

Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

RTECSTX4200000

Precautionary statements

P273 Avoid release to the environment. 避免释放到环境中。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P305+P351+P338
P201 Obtain special instructions before use. 使用前获取专门指示。
P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P302+P352+P333+P313+P362+P364
P308+P313
P501 Dispose of contents/container to..… 处理内容物/容器.....
P301+P312+P330
P337+P313
P403+P233

Signal word

UN Number UN3271

Risk Statements

R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
R10 Flammable 易燃
R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
R52/53
R37 Irritating to respiratory system 刺激呼吸道
R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害

Safety Statements

S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
S53 Avoid exposure - obtain special instructions before use 避免接触，使用前获得特别指示说明；
S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；

Packing GroupIII

Hazard Class3

Storage condition Moisture Sensitive

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 260 mg/m3
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - dyspnea
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 51(8),91,1986

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1030 ppm/8H
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - lacrimation
   Gastrointestinal - changes in structure or function of salivary glands
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   AMIHAB AMA Archives of Industrial Health.  (Chicago, IL)  V.11-21, 1955-60.
   For publisher information, see AEHLAU.  Volume(issue)/page/year: 14,250,1956

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >2150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TSCAT* Office of Toxic Substances Report.  (U.S. Environmental Protection
   Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
   Volume(issue)/page/year: OTS0515483

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - somnolence (general depressed activity)
   Behavioral

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 1 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 231,205,1990

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 20 umol/L
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   46,277,1980

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 2500 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 249,55,1991

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 675 mg/kg
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 2,521,1980

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 10 mg/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 66,367,1979

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 1 umol/L
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 36 gm/kg
SEX/DURATION            : male 24 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 124,225,1983

其他信息

毒性分级:中毒
Sigma Aldrich:2426-08-6(sigmaaldrich)
储运特性:库房通风低温干燥; 与氧化剂分开存放
爆炸物危险特性:闪点以上; 与空气混合可爆炸
图谱信息:正丁基缩水甘油醚(2426-08-6)质谱(MS) 正丁基缩水甘油醚(2426-08-6)Raman光谱正丁基缩水甘油醚(2426-08-6)核磁图( 1 HNMR) 正丁基缩水甘油醚(2426-08-6)红外图谱(IR1) 正丁基缩水甘油醚(2426-08-6)核磁图( 13 CNMR)
急性毒性:口服-大鼠 LD50: 2050 毫克/公斤; 口服-小鼠 LD50: 1520 毫克/公斤
用途一:环氧树脂活性稀释剂，有增韧作用，还可作为聚氯乙烯的稳定剂和增塑剂
类别:易燃液体
上游原料:氢氧化钠 --> 乙醚 --> 正丁醇 --> 环氧氯丙烷 --> 三氟化硼乙醚 --> 二丁醚 --> 四丁基硫酸氢铵
方法一:由丁醇和环氧氯丙烷为原料，经两步反应合成。具体工艺过程为：将267kg丁醇和32kg浓度为96%的浓硫酸加入反应釜，搅拌，升温至55℃，滴加环氧氯丙烷324kg，温度控制在55-60℃约4h加完，再在60-65℃保温2h。然后，冷却至45℃，缓缓加入四氯化锡与丁醇的混合液（5kg四氯化锡溶于5kg丁醇中），再在60-65℃保温反应4h，反应完后，减压蒸馏回收未反应的环氧氯丙烷和丁醇，直至温度达到85-95℃，真空度93.1kPa下无环氧氯丙烷和丁醇蒸出为止。得到表氯醇丁基醚。将上述反应物料冷至30-35℃，滴加浓度30%的氢氧化钠432kg，约4h加完，然后升温至35-40℃并保温反应3h，再在搅拌下加入纯苯，升温至放掉盐水和碱水，然后水洗使pH约为6.5-7。放掉洗涤水，升温常压脱苯，直至料液温度达至140℃，然后冷却放料。两步总收率以丁醇计约为95%。
刺激数据:皮肤-兔 454 毫克/3天轻度; 眼睛-兔 0.75 毫克/24小时重度
MSDS 信息:2,3-环氧丙基丁醚(2426-08-6).msds
外观性质:无色液体。
MOL 文件:2426-08-6.mol
TCI Shanghai:正丁基缩水甘油醚 Butyl Glycidyl Ether,>;98.0%(GC)(2426-08-6)
Alfa Aesar:正丁基缩水甘油醚,95% n-Butyl glycidyl ether, 95%(2426-08-6)
用途三:该品可作双酚A环氧树脂的活性稀释剂。毒性小，使用方便。并能改善一些树脂硬化后的性能，如抗冲强度等。
F:9-21
正丁基缩水甘油醚价格(试剂级):更新日期产品编号产品名称包装价格 2014/06/02 B0697 丁基缩水甘油醚 Butyl Glycidyl Ether 500ML 470元 2014/06/02 B0697 丁基缩水甘油醚 Butyl Glycidyl Ether 25ML 170元 2010/05/25 L16201 正丁基缩水甘油醚, 95% n-Butyl glycidyl ether, 95% 50ml 161元
海关编码:29109000
用途二:用作活性稀释剂
职业标准:TWA 135 毫克/立方米; STEL 200 毫克/立方米
灭火剂:水, 干粉, 二氧化碳, 泡沫
可燃性危险特性:易燃; 热分解排出辛辣刺激烟雾