2'-(4-Ethoxyphenyl)-5-(4-Methylpiperazin-1-Yl)-1H,1'H-2,5'-Bibenzo[D]Imidazole 2’-(4-乙氧基苯基)-5-(4-甲基哌嗪-1-基)-1H,1’H-2,5’-联苯并[d]咪唑
CAS 23491-52-3 MFCD00012678
化学结构图
SMILES: Cl.Cl.Cl.CN1CCN(CC1)C1=CC2N=C(NC=2C=C1)C1=CC2N=C(NC=2C=C1)C1C=CC(=CC=1)OCC
化学属性
| Mol. Formula | C27H28N6O · 3HCl · xH2O |
|---|---|
| Mol. Weight | 561.93 (anhydrous basis) |
别名和识别编码
| Chemical Name | 2'-(4-Ethoxyphenyl)-5-(4-Methylpiperazin-1-Yl)-1H,1'H-2,5'-Bibenzo[D]Imidazole |
|---|---|
| Synonym | HOE 33342; 2'-(4'-Ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bis-1H-benzimidazole trihydrochloride trihydrate |
| CAS Number | 23491-52-3 |
| PubChem Substance ID | 57647173 |
| Beilstein Registry Number | 1234011 |
| MDL Number | MFCD00012678 |
| EC Number | 245-691-1 |
| Chemical Name Translation | 2’-(4-乙氧基苯基)-5-(4-甲基哌嗪-1-基)-1H,1’H-2,5’-联苯并[d]咪唑 |
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分类
- {SNA} Alphabetical, Detection,
- {SA} Alphabetical, Biochemicals and Reagents, Detection, Fluorescent Probes, Labels, Particles and Stains, Fluorescent Stains, Luminescent Compounds/Detection,
- {SNA} Alphabetical, Apoptosis Detection, Apoptosis and Cell Cycle, B, Core Bioreagents, Fluorescent Stains, General Reagents, Life Science Reagents for RNAi, Nucleic Acid Stains, Reagents, Research Essentials, Stains & Dyes, A to Z, Stains and Dyes, 生化试剂, 细胞信号转导和神经科学, 细胞生物学, 荧光探针，标记，粒子和染色剂,
相关文献及参考
- Crissman, H.A., and Steinkamp, J.A., Exp. Cell Res. 173 , 256, (1987) 摘要
- Latt, S.A. and Stetten, G. J. Histochem. Cytochem. 24 , 24, (1976)
- Merck 14 ,10367
安全信息
GHS Symbol
- H315 Causes skin irritation 会刺激皮肤
- H318 Causes serious eye damage 严重伤害眼睛
- H302 Harmful if swallowed 吞食有害
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
- S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
- S37 Wear suitable gloves 戴适当手套；
- S22 Do not breathe dust 不要吸入粉尘；
- R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
- R22 Harmful if swallowed 吞咽有害
TYPE OF TEST : DNA damage TEST SYSTEM : Rodent - hamster Lung DOSE/DURATION : 1 umol/L REFERENCE : JHCYAS Journal of Histochemistry and Cytochemistry. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1953- Volume(issue)/page/year: 30,111,1982
TYPE OF TEST : DNA damage TEST SYSTEM : Rodent - mouse Fibroblast DOSE/DURATION : 5 umol/L REFERENCE : CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 9,485,1988
TYPE OF TEST : DNA inhibition TEST SYSTEM : Human HeLa cell DOSE/DURATION : 300 nmol/L REFERENCE : CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 13,2389,1992
TYPE OF TEST : DNA inhibition TEST SYSTEM : Rodent - hamster Lung DOSE/DURATION : 1 umol/L REFERENCE : JHCYAS Journal of Histochemistry and Cytochemistry. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1953- Volume(issue)/page/year: 30,111,1982
