3-Indoleglyoxylyl Chloride 吲哚-3-乙醛酰氯

CAS 22980-09-2 MFCD00015460

化学结构图

22980-09-2
SMILES: O=C(Cl)C(=O)c1c[nH]c2ccccc12

化学属性

Mol. FormulaC10H6ClNO2
Mol. Weight207.61
Melting Point138 °C (dec.)(lit.)
TSCANo

别名和识别编码

Chemical Name3-Indoleglyoxylyl Chloride
CAS Number22980-09-2
Synonym 吲哚-3-乙醛酰氯 NSC 128332 (1H-Indol-3-yl)oxoacetyl Chloride α-Oxoindole-3-acetyl chloride α-Oxoindole-3-acetyl chloride alpha-Oxoindoleacetyl chloride 2-(3-Indolyl)-2-oxoacetyl Chloride alpha-Oxo-1H-indole-3-acetyl chloride ?-Oxo-1H-indole-3-acetyl Chloride 2-(3-Indolyl)-2-oxoacetyl chloride 3-Indoleglyoxylyl Chloride α-Oxoindole-3-acetyl chloride 2-(3-Indolyl)-2-oxoacetyl chloride NSC 128332
MDL NumberMFCD00015460
PubChem Substance ID24873804
EC Number245-362-2
Beilstein Registry Number147693
Chemical Name Translation吲哚-3-乙醛酰氯
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分类

  • {SNA} Building Blocks, C10, Chemical Synthesis, Heterocyclic Building Blocks, Indoles
  • Building Blocks, C10, Chemical Synthesis, Heterocyclic Building Blocks, Indoles

产品应用

  • An indole derivative used in the preparation of reagents for chemiluminescent enzyme immunoassay. It is an impurity in the manufacture of tryptamines and related compounds.

相关文献及参考

  • Nakazono, M. et al.: Anal. Sci., 19, 123 (2003); Cowie, J.S. et al.: J. Forensic Sci., 27, 527 (1982);
  • 1. Schmidt, S.; et al. Eur. J. Med. Chem. 46 , 2759, (2011)
  • 2. Chauhan, S., S.; et al. Bioorg. Med. Chem. Lett. 20 , 6191, (2010)
  • 3. Kutschy, P.; et al. Collect. Czech. Chem. Commun. 75 , 887, (2010)
  • 4. Feldman, K., S.; Ngernmeesri, P. Org. Lett. 12 , 4502, (2010)
  • 5. Wang, T; et al. J. Med. Chem. 52 , 7778, (2009)
  • 6. Aubry, C.; et al. Bioorg. Med. Chem. 17 , 6073, (2009)
  • Beil. 22 ,II,248

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
Signal word Danger
Hazard statements
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
Hazard Codes C
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S27 Take off immediately all contaminated clothing 立即脱掉全部污染的衣服;
UN Number UN2923
Risk Statements
  • R34 Causes burns 会导致灼伤
  • R23 Toxic by inhalation 吸入有毒
Storage condition Moisture Sensitive
Packing GroupII

系列性分类


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